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  • Safety and Environmental Considerations in the Life Sciences Laboratory

    Friday, September 05, 2014
    Application Note
    Larry Gallagher
    In life science laboratories and biotech firms, safety and environmental issues can be presented by the gases and cryogens utilized in the processes and controls. From simple oxygen deficiency that ... read more

  • Particle Characterization: Challenges Associated With Submicrometer-Sized Objects

    Wednesday, April 02, 2014
    Application Note
    Craig S. Schwandt
    Materials in the form of particulate or engineered objects are relatively easy to characterize in terms of their composition, shape, size, and size distribution, provided they are larger than 1 µm in... read more

  • Integrating Microscopy Into the Analytical Scheme: A Pittcon® 2014 Microscopy Review

    Monday, February 24, 2014
    Technical Article
    Barbara Foster
    Microscopy is often overlooked at Pittcon®, yet of the 12,000+ scientists who attend, approximately 30% use microscopy in some form (according to ongoing research from The Microscopy & Imaging Place, ... read more

  • Improved Long-Term Culture Using A Microfluidic Platform

    Monday, October 07, 2013
    Application Note
    Alex Mok Paul Hung Cindy Chen Sónia Gil Kathleen Ongena
    Precise and biologically relevant in vitro studies require the ability to analyze cell responses to perturbations over time. In order to achieve successful long-term cell culture and imaging, however,... read more

  • Multiparameter Pluripotency Analysis Using Magnetic Bead Assays

    Wednesday, August 28, 2013
    Application Note
    Nikolai Stankiewicz Thomas Siegl Frederick Wiese
    For the application of induced pluripotent stem cells (iPSCs) and human embryonic stem cells (hESCs) to regenerative medicine and drug discovery research, it is crucial to characterize the identity ... read more

  • Product Intelligence: Stereomicroscope Technology

    Tuesday, May 28, 2013
    Technical Article
    Katriona Scoffin
    Stereomicroscopes find application in many areas of science, such as pharmaceutical, environmental, forensics, and foods. A common use of the stereomicroscope is to magnify biological samples. This ... read more

  • Putting the “More” in Morphology: Part 2

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Part 1 of this article discussed the impact of multiplexing morphological methods, multiparametric techniques, and supervised machine-learning to answer the question "what" is there, as well as "where... read more

  • A High-Resolution Look at Glass Delamination Using Transmission Electron Microscopy (TEM)

    Tuesday, April 09, 2013
    Technical Article
    Elaine F. Schumacher
    Formation of glass delamination flakes and secondary products through reaction of injectable pharmaceutical solutions with glass vial packaging leads to product contamination and costly recalls. ... read more

  • Use of an Environmental Transmission Electron Microscope for Dynamic in situ Studies of Nano-...

    Thursday, March 07, 2013
    Application Note
    Joerg R. Jinschek
    Current research and development (R&D) that is focused on efficient energy conversion and environmental protection technologies relies heavily on advances in the development of new and improved ... read more

  • Microscopy + Spectroscopy: Pittcon® 2013 Celebrates the Power of Two

    Thursday, March 07, 2013
    Technical Article
    Barbara Foster
    The year 2013 celebrates a new benchmark for imaging at Pittcon®. Historically, Pittcon has not been considered an imaging meeting, despite the fact that a review of Pittcon 2012 statistics revealed ... read more

  • Product Intelligence: Buyers' Guide to Biological Confocal Microscopes

    Thursday, May 24, 2012
    Technical Article
    T. Keith Brock
    Confocal microscopes offer the user a number of important advantages, including high resolution, ability to electronically adjust magnification, and improved signal-to-noise ratios. In addition, the ... read more

  • Microscopy: Imaging Broader, Diving Deeper

    Monday, April 09, 2012
    Technical Article
    Barbara Foster
    In previous articles and editorials, the life sciences have been defined as the “next big growth area” in microscopy, spectroscopy, and related imaging techniques. read more

  • New Solutions for Surface Texture Analysis

    Monday, November 01, 2010
    Technical Article
    Barbara Foster
    Most microscopists are familiar with confocal microscopy from neuroscience or cell biology. However, very quietly and abruptly, confocal has jumped the fence into industry, becoming a major tool-of-... read more

  • Effective Forensic Sample Tracking and Handling

    Wednesday, September 01, 2010
    Application Note
    Tal Murthy Brian Hewson
    With implications for the success of a legal case, forensic samples must be stored under optimal conditions to avoid DNA deterioration. Failure to maintain proper storage conditions can result in ... read more

  • Confidence Up Close

    Friday, January 01, 2010
    Application Note
    Aubrey Lambert
    The combined pressures of continuing miniaturization, higher packing densities, and rigorous quality assurance means that the physical size of particles capable of adversely affecting industrial ... read more

  • Fish-Related Standard Reference Materials

    Sunday, February 01, 2009
    Technical Article
    Michele Schantz Stephen A. Wise Steven J. Christopher W. Clay Davis Rusty D. Day Jennifer M. Keller John R. Kucklick Stephen E. Long Elizabeth A. Mackey David Point Barbara J. Porter Dianne L. Poster Katherine E. Sharpless Gregory C. Turk
    Humans have been eating fish for thousands of years, enjoying its nutritional benefits. In extreme cases, health risks posed by contaminants can outweigh the health benefits imparted by fish ... read more

  • Statistics in Analytical Chemistry: Part 25—Calibration Summary

    Thursday, February 01, 2007
    Technical Article
    David Coleman Lynn Vanatta
    In a modern chemical-analysis laboratory, virtually all of the testing equipment must be calibrated periodically. read more

  • Centrifuge Safety and Security

    Thursday, February 01, 2007
    Application Note
    Tammy Goodman
    For laboratories around the world, increasing health and safety legislation requires that equipment be operated and maintained so that every step is taken to maximize safety and security. read more

  • Reagent-Free Ion Chromatography Systems With Eluent Regeneration: RFIC-ER Systems

    Thursday, February 01, 2007
    Application Note
    Yan Liu Zhongqing Lu Chris Pohl John Madden Navette Shirakawa
    Since the introduction of ion chromatography (IC) in 1975, Dionex Corp. (Sunnyvale, CA) has continued to improve the performance of IC systems while developing new capabilities for the determination ... read more

  • The Nanoliter Syringes

    Thursday, February 01, 2007
    Technical Article
    Andrew D. Sauter
    Following an informal collaboration with Affymax (Palo Alto, CA), Agilent Technologies (Palo Alto, CA), and Chem-Space Associates (Pittsburgh, PA), studying electrospray ionization 1 (ESI), the ... read more
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