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  • Analytical Method Development in the Quality by Design Framework

    Tuesday, December 16, 2014
    Application Note
    Torgny Fornstedt Dennis Åsberg Jörgen Samuelsson Anders Karlsson Krzysztof Kaczmarski
    The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ... read more

  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more

  • R&D Informatics at Molecular Med Tri-Con 2013

    Tuesday, February 26, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in... read more

  • Ask the Expert: Using Rheology to Design Better Products—Yield Stress and How to Measure It

    Tuesday, July 24, 2012
    Application Note
    John Duffy
    Successfully manipulating the rheology of a product during its development enables formulators to deliver desirable characteristics—the right feel and texture, great stability, and optimal usability ... read more

  • Small-Scale Vane Rheometry

    Tuesday, August 02, 2011
    Application Note
    David Moonay
    Vane rheometry continues to become more well-known and popular. read more

  • Drying of Problematic Purification Samples by Lyophilization in a Centrifugal Evaporator

    Monday, June 13, 2011
    Application Note
    Induka Abeysena Rob Darrington
    Lyophilization is often the preferred method of sample drying because a high level of dryness is achieved with low residual solvent levels, and because of the light, powdery, “fluffy” finish of the ... read more

  • Are You Attracted to Science? Attend Pittcon®—The Magnet for Scientific Innovation

    Tuesday, February 01, 2011
    Technical Article
    Penny. R Gardner
    We are very excited for Pittcon® 2011 to be back in Atlanta, GA, March 13–18, at the Georgia World Congress Center. read more

  • Use of Rotational Vane Rheometry to Solve Practical Problems

    Saturday, August 01, 2009
    Application Note
    David J. Moonay
    Rheology is the study of the deformation of matter. A common definition is that rheology is the study of flow. Viscometry, in particular, is the measurement of viscosity or the resistance to flow. ... read more

  • Redefining the Rheometer

    Monday, October 27, 2008
    Application Note
    Steve Carrington
    The way in which materials flow or deform when a force is applied can have a direct impact on product performance. read more

  • Measuring Yield Stress

    Thursday, November 01, 2007
    Technical Article
    Richard Buscall Adrian Hill
    Various materials, typically gels or dispersions with a high concentration of suspended particles, can behave either as elastic solids or as liquids, depending on the degree of force or stress to ... read more

  • Statistics in Analytical Chemistry: Part 25—Calibration Summary

    Thursday, February 01, 2007
    Technical Article
    David Coleman Lynn Vanatta
    In a modern chemical-analysis laboratory, virtually all of the testing equipment must be calibrated periodically. read more

  • Centrifuge Safety and Security

    Thursday, February 01, 2007
    Application Note
    Tammy Goodman
    For laboratories around the world, increasing health and safety legislation requires that equipment be operated and maintained so that every step is taken to maximize safety and security. read more

  • Reagent-Free Ion Chromatography Systems With Eluent Regeneration: RFIC-ER Systems

    Thursday, February 01, 2007
    Application Note
    Yan Liu Zhongqing Lu Chris Pohl John Madden Navette Shirakawa
    Since the introduction of ion chromatography (IC) in 1975, Dionex Corp. (Sunnyvale, CA) has continued to improve the performance of IC systems while developing new capabilities for the determination ... read more

  • The Nanoliter Syringes

    Thursday, February 01, 2007
    Technical Article
    Andrew D. Sauter
    Following an informal collaboration with Affymax (Palo Alto, CA), Agilent Technologies (Palo Alto, CA), and Chem-Space Associates (Pittsburgh, PA), studying electrospray ionization 1 (ESI), the ... read more

  • Flow Characterization: Selecting Appropriate Technology

    Tuesday, November 01, 2005
    Application Note
    Steve Carrington Joanne Langridge
    It is well known that measuring the rheological properties of materials contributes to the development of better products and helps predict end-use performance as well as the physical properties of a... read more
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