Technical Articles

There are times when an analytical challenge demands a solution that reaches beyond standard methodologies. read more

The previous two installments have discussed the issue of nonideal recovery, a problem that occurs in many analytical methods. read more

The volume of HPLC mobile phase (MP) purchased and discarded each year is about 20,000,000 L, or enough to fill two rail trains each with 100 tank cars. On average, each of the 200,000 active HPLCs... read more

Since the beginning of this series of articles, the central topic has been calibration and its associated uncertainty. read more

Sample introduction has been a problem for analytical chemists for decades. In 1984, Richard Browner and Andrew Boorn went so far as to call sample introduction "The Achilles’ Heel of Atomic ... read more

In the previous article (Part 22, American Laboratory, June/July 2006), the details behind the lack-of-fit (LOF) test were discussed. read more

High-speed calorimetry, and specifically high-speed differential scanning calorimetry (DSC), has received a great deal of attention in recent years. read more

Because of popular demand from readers, this installment will discuss the principles and calculations that underlie the lack-of-fit (LOF) test. read more

In the biotechnology industry, traditional sodium dodecyl sulfate-polyacrylamide gel electrophoresis(SDS-PAGE)has been widely used to monitor the integrity and purity of therapeutic proteins during ... read more

The quality control (QC) unit of any global supply chain for a large corporate entity is responsible for the testing of products and materials across all manufacturing sites within the supply chain, ... read more