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Title
The Role of Analytical Instrumentation in the Life Sciences
Saturday, November 01, 2008
Robert L. Stevenson, Ph.D.
C. David Carr
Historically, the life sciences have been qualitative in nature, seeking to identify but seldom understand quantitatively.
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What is “Hot” in Column Technologies for Liquid Chromatography?
Thursday, December 04, 2008
Frantisek Svec
It has been just over 100 years since Russian botanist Mikhail Semionovich Tswett invented the separation technique that he named chromatography.
read more
Making Single-Molecule Sequencing a Reality
Friday, December 05, 2008
Avak Kahvejian
Steve Kellett
The quest to directly sequence individual strands of DNA has challenged genomic technologists for decades.
read more
Desktop Biological Nanopatterning Using Dip-Pen Nanolithography
Friday, December 05, 2008
Jason Haaheim
Omkar A. Nafday
The ability to control the size and shape of deposited chemical structures on the nanoscale opens up new and exciting possibilities for the development of devices for use in the electronic, life ...
read more
An Immunoaffinity Capillary Electrophoresis Biomarker Analyzer for Use in Toxicoproteomics Research
Friday, December 05, 2008
Norberto A. Guzman
The slow pace of discovery of new protein biomarkers of toxicity or “toxicity signature protein/peptides” is partially due to the lack of high-throughput and high-sensitivity biomarker devices.
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WS-CRDS: Precision Trace Gas Analysis and Simplified Stable Isotope Measurements
Friday, December 05, 2008
Eric R. Crosson
Wavelength-scanned cavity ring-down spectroscopy (WSCRDS) is fast gaining worldwide acceptance as a superior tool for trace gas analysis, because it combines operational simplicity and portability ...
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Statistics in Analytical Chemistry: Part 32—Detection Limits Via 3-Sigma
Friday, December 05, 2008
David Coleman
Lynn Vanatta
As was mentioned in the first article on detection limits (DLs) (Part 26, American Laboratory, June/July 2007), many formulas exist for calculating these values.
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Fritless Chromatographic Microfluidic-Based Columns for Chemical Separations
Monday, October 27, 2008
Frank A. Gomez
Attila Gaspar
Shima Baghdachi
Mark Goldberg
Schetema Stevens
Jaime Torres
Marisol Salgado
The development of microfluidic chips and devices offers a number of advantages over conventional analytical techniques, including small sample volume requirements, portability, fast sampling times, ...
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Unlocking the Secrets of Automation in the Pharmaceutical Laboratory
Monday, October 27, 2008
Abe Kassis
Tarun Patel
Kevin Bynum
Roy Paul
A brief discussion about dissolution is important to understand the relevance of automation to this field.
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Measurement of Viscosity in a Vertical Falling Ball Viscometer
Monday, October 27, 2008
Ping Yuan
Ben-Yuan Lin
A number of methods are used to measure the viscosity of fluids.
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Quality Evaluation of HPLC-Grade Acetonitrile
Monday, September 01, 2008
Shi-heng Liu
Acetonitrile is the most commonly used organic mobile phase component due to its unique properties that set it apart from the other LC solvents (midrange solvent strength, excellent solvent ...
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Detection of Chemical Warfare Agents on Surfaces Relevant to Homeland Security by Direct Analysis in Real-Time Spectrometry
Monday, September 01, 2008
H. Dupont Durst
J. Michael Nilles
Theresa R. Connell
James A. Laramée
Analysis of low-volatility, condensed- phase chemicals on surfaces has been an extremely difficult and long-standing objective in environmental monitoring.
read more
Celebrating 25 Years of Inductively Coupled Plasma-Mass Spectrometry
Friday, September 26, 2008
Jeanely Hunt, MS, MBA
2008 marked the 25th anniversary of inductively coupled plasma-mass spectrometry (ICP-MS).
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Statistics in Analytical Chemistry: Part 31—Receiver Operating Characteristic (ROC) Curves: Equations
Friday, September 26, 2008
David Coleman
Lynn Vanatta
Please do not despair! This article is not a series of formulas to be memorized.
read more
Advances in Accurate-Mass TOF and Q-TOF LC-MS Systems
Friday, August 29, 2008
Ken Imatani
Due to the growing interest in the comparative analysis of biological samples in the fields of biomarker discovery and metabolomics, the complexity of samples faced by researchers is greater than ever...
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Nanoparticle Measurement Through Visualization
Friday, August 29, 2008
Bob Carr
Andrew Malloy
The analysis of nanoparticles is a ubiquitous requirement in a broad range of industry sectors.
read more
Characterization of D-Mannitol by Thermal Analysis, FTIR, and Raman Spectroscopy
Friday, August 29, 2008
Peng Ye
Thomas Byron
D-mannitol is a common excipient used in the pharmaceutical formulation of tablets.
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Statistics in Analytical Chemistry: Part 30—Statistically Derived Detection Limits (Concluded)
Thursday, July 10, 2008
David Coleman
Lynn Vanatta
In Part 29 (American Laboratory, Feb 2008), Hubaux-Vos detection limits (H-V DLs) were explained and an illustration was given.
read more
Development of a New Platform of Highly Inert Fused-Silica Capillary Columns
Thursday, July 10, 2008
Jaap de Zeeuw
Gary Stidsen
Roy Lautamo
Chris English
Shawn Reese
Gas chromatography technology has consistently improved sensitivity for difficult-to-analyze compounds.
read more
A Compact Benchtop FTIR Spectrometer for the Academic Laboratory
Thursday, July 10, 2008
Thomas J. Tague, Jr.
Albrecht Rager
Paul Turner
Fourier transform infrared spectrometers (FTIRs) currently used in colleges and universities have several limitations.
read more
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