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Identifying Pharmaceuticals in Surface Water Using LC-MS/MS in Both Positive and Negative Ion Modes
Compounds such as antibiotics, over-the- counter medicines, and caffeine drain through the sewage system largely unaltered into rivers and streams, and even enter the drinking water supply in very ...
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A GC Tool to Ensure Precise GC Column Installation for Method Sensitivity and Reproducibility
Correct and precise gas chromatography column installation is critical to system performance. Columns that are installed at an improper or inconsistent depth will adversely affect analyte response and...
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Measuring the Heat of Evaporation by TGA/DSC
Heat of evaporation is the amount of heat required to make a physical change from the liquid phase to the gas phase.
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Using Light Scattering to Characterize SiO2 Chemical Mechanical Planarization Slurries
Chemical mechanical planarization (CMP) slurries are typically colloidal dispersions of silicon dioxide (SiO2) in an acid or base solution. They are integral to the semiconductor industry, emerging as...
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The Use of Pressurized Liquid Dispensing Containers (PLDCs) With Flammable Liquids in Laboratories
Large quantities of flammable solvents are used in today’s high-throughput analytical and biopharmaceutical laboratories. To minimize hazards, these laboratories have tried to adopt alternative ...
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Solutions for Global Health and Well-Being
From investigating mercury-laden tuna sushi in Manhattan to high-profile recalls of contaminated toys and international concern over the quality of water and air in the 2008 Olympic Village, meeting ...
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Sub-2-Micron Performance With a Conventional HPLC Instrument Using 2.7-Micron Fused Core Particles
Ultrahigh-performance liquid chromatography (UHPLC) utilizes sub-2-µm-diam stationary phase particles to provide improved performance over conventional HPLC. This can be realized either in a higher ...
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Key Requirement Differences for Electronic Notebooks in Discovery, Development Research, and cGMP Manufacturing Environments
Many leading life science companies have cost reduction initiatives to eliminate the routine, nonvalueadded tasks through automation. In most regulated companies, approximately 70% of laboratory-based...
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Simply Intelligent: A Next-Generation Chromatography Data System
Chromatography data systems perform many complex tasks, including instrument control, data capture, qualitative and quantitative data analysis, and report generation. To perform these tasks ...
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Reliable and Effective Trace-Level Total Sulfur Determination Using New Injection and Combustion Technologies
Total sulfur and nitrogen (TS/TN) levels are commonly used parameters in the petrochemical, natural gas, and oil refining industries, and the need for their determination is growing due to the ...
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Alcohols Can Now Be Analyzed by a Direct Analysis in Real-Time Method: Applications for Chemical Warfare Agent Synthesis
The cardinal principle for an operation involving chemical agents is to limit the potential exposure to a minimum number of personnel, for a minimum period of time, to a minimum amount of the ...
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A Fully Automated Benchtop X-Ray Diffractometer for Structure Determination of Small Molecules
Single-crystal crystallography provides accurate and precise measurements of molecular dimensions in a way that no other science can begin to approach. Small-molecule crystallographers study ...
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Food Safety: The Value of LIMS in This Regulated Environment
The U.S. Food and Drug Administration (FDA) has issued a number of regulations to ensure the safety of food manufactured, distributed, exported, and imported in the U.S. The Federal Food, Drug and ...
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Focus on Microscopy: One Button and Two Heads—Mainstreaming AFM
The past decade has seen dramatic growth in scanning probe microscopy (SPM) technology, both in functionality and in broader acceptance. Market research conducted in mid-2007 by The Microscopy and ...
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Antifungal, Insecticidal, Cytotoxicity, and Phytotoxicity Studies of Binuclear Ni(II) and Cu(II) Complexes of Diclofenac
Diclofenac, a nonsteroidal antiinflammatory drug (NSAID), is one of the most frequently used medicines for the treatment and management of pain and edema associated with rheumatoid arthritis, ...
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