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  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more

  • How Solid-Phase Extraction Affects Challenges in Bioanalysis

    Wednesday, February 05, 2014
    Application Note
    Mike Oliver Tim Liddicoat Ken Meadows
    Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more

  • Product Intelligence: Solid Phase Extraction Systems

    Monday, February 25, 2013
    Technical Article
    Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more

  • Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more

  • Matrix Degradation Assays for Investigating Cell Invasion

    Tuesday, November 01, 2011
    Application Note
    Jun Ma Luke Armstrong Janet Anderl
    Tumor metastasis, inflammation, and development are accompanied by the invasion of cells through the extracellular matrix. read more

  • The State of Microscopy for 2012

    Tuesday, November 01, 2011
    Technical Article
    Barbara Foster
    In various recent interviews, I’ve been asked about the state of microscopy and, most specifically, the rise of technologies such as AFM (atomic force microscopy) and Raman confocal and the ... read more

  • Managing Laboratory Maintenance

    Tuesday, February 07, 2006
    Application Note
    L. Wayne Collins
    Other than personnel-related costs, maintenance is generally the most expensive item in the laboratory operating budget. read more

  • Defragmenting Chiral Chromatography

    Wednesday, February 01, 2006
    Application Note
    Regina Valluzzi Benjamin Chaloner-Gill
    Chiral molecules continue to drive growth across a number of industries as new chemistries, active ingredients, and products are developed and commercialized. read more

  • Reflections on a Third-Generation Mobile Phase Recycler for HPLC

    Wednesday, February 01, 2006
    Technical Article
    Al Welch
    The volume of HPLC mobile phase (MP) purchased and discarded each year is about 20,000,000 L, or enough to fill two rail trains each with 100 tank cars. On average, each of the 200,000 active HPLCs... read more

  • Statistics in Analytical Chemistry: Part 20—Recovery Curves

    Wednesday, February 01, 2006
    Technical Article
    David Coleman Lynn Vanatta
    In Part 19 of this series (American Laboratory Dec 2005), the use of an internal standard (IS) was discussed and an example was given. read more

  • Dynamic Light Scattering For the Noninvasive Detection of Protein Aggregation

    Wednesday, February 01, 2006
    Application Note
    Bernard Lorber
    Protein homogeneity is an important issue in many fields of research, be it the characterization of newly isolated molecules, the identification of crystallizable samples, or the preparation of ... read more

  • Single-Step Purification of Lactase From a New Isolate of L. acidophilus

    Wednesday, February 01, 2006
    Application Note
    Sameer K. Akolkar Smita S. Lele
    Lactase (ß-D-galactohydrolase EC 3.2.1.23) is widely distributed in microorganisms, plants, and animals. read more
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