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  • Analytical Method Development in the Quality by Design Framework

    Tuesday, December 16, 2014
    Application Note
    Torgny Fornstedt Dennis Åsberg Jörgen Samuelsson Anders Karlsson Krzysztof Kaczmarski
    The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ... read more

  • Safety and Environmental Considerations in the Life Sciences Laboratory

    Friday, September 05, 2014
    Application Note
    Larry Gallagher
    In life science laboratories and biotech firms, safety and environmental issues can be presented by the gases and cryogens utilized in the processes and controls. From simple oxygen deficiency that ... read more

  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more

  • R&D Informatics at Molecular Med Tri-Con 2013

    Tuesday, February 26, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in... read more

  • Drying of Problematic Purification Samples by Lyophilization in a Centrifugal Evaporator

    Monday, June 13, 2011
    Application Note
    Induka Abeysena Rob Darrington
    Lyophilization is often the preferred method of sample drying because a high level of dryness is achieved with low residual solvent levels, and because of the light, powdery, “fluffy” finish of the ... read more

  • Are You Attracted to Science? Attend Pittcon®—The Magnet for Scientific Innovation

    Tuesday, February 01, 2011
    Technical Article
    Penny. R Gardner
    We are very excited for Pittcon® 2011 to be back in Atlanta, GA, March 13–18, at the Georgia World Congress Center. read more

  • Effective Forensic Sample Tracking and Handling

    Wednesday, September 01, 2010
    Application Note
    Tal Murthy Brian Hewson
    With implications for the success of a legal case, forensic samples must be stored under optimal conditions to avoid DNA deterioration. Failure to maintain proper storage conditions can result in ... read more

  • Fish-Related Standard Reference Materials

    Sunday, February 01, 2009
    Technical Article
    Michele Schantz Stephen A. Wise Steven J. Christopher W. Clay Davis Rusty D. Day Jennifer M. Keller John R. Kucklick Stephen E. Long Elizabeth A. Mackey David Point Barbara J. Porter Dianne L. Poster Katherine E. Sharpless Gregory C. Turk
    Humans have been eating fish for thousands of years, enjoying its nutritional benefits. In extreme cases, health risks posed by contaminants can outweigh the health benefits imparted by fish ... read more

  • Aligning Ultrafast NMR Spectroscopy and Cold Probe Technology to Reveal the Mysteries of Protein ...

    Wednesday, March 01, 2006
    Application Note
    Judit Losonczi Eriks Kupce George Gray Peter Sandor Bernhard Brutscher
    The understanding of protein dynamics, the way these molecules fold to form a stable structure, interact with other molecules, or undergo changes during enzyme activity, etc., in their native ... read more

  • Procurement and Supply of Cell Storage Systems for the Biotechnology Laboratory

    Thursday, December 01, 2005
    Technical Article
    Steve Scheuring Jim Gordon
    Specifying a cell storage system is an important decision for any life sciences laboratory. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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