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  • Automated Botulinum Neurotoxin Detection

    Automated Botulinum Neurotoxin Detection

    Monday, February 25, 2013
    Technical Article
    Karine Bagramyan, Aneela Reddy, Dobrin Nedelkov, Markus Kalkum
    Botulinum neurotoxin (BoNT) is undoubtedly the most potent biological toxin known. Intravenously injected it could paralyze and kill a human being at a dose of just 1.2 ng BoNT per kg body weight. read more
  • Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Friday, February 08, 2013
    Technical Article
    Robert L. Stevenson
    Most commonly, laboratory automation involves a few hundred wells run for a specific purpose. SLAS 2013, the meeting of the Society for Laboratory Automation and Screening, was held at the Gaylord ... read more
  • Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Thursday, January 17, 2013
    Application Note
    Robert L. Stevenson
    Expanded bed adsorption (EBA) was introduced in 1999 with adsorbents that were used for pressure-driven packed beds. These had densities in the range of 1.1–1.5 g/mL, which was not much higher than ... read more
  • Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Monday, December 24, 2012
    Technical Article
    Laurent Baron, Bobby Chavli, Lois Tack, Annette Summers
    For years, forensic laboratories in the U.S. have struggled to reduce DNA sample processing backlogs and human errors, both of which hinder timely and reliable criminal convictions. read more
  • Optimizing HPLC Sample Preparation

    Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more
  • Light-Emitting Diodes: A New Solution for Fluorescence

    Light-Emitting Diodes: A New Solution for Fluorescence

    Saturday, October 01, 2011
    Technical Article
    Barbara Foster
    From the dramatic increase in new fluorophores to the proliferation of techniques like total internal reflection fluorescence (TIRF), photoactivated localization microscopy (PALM), and stochastic... read more
  • Microscopy in 2011: The Imaging Suite is the Microscope

    Microscopy in 2011: The Imaging Suite is the Microscope

    Thursday, April 07, 2011
    Application Note
    Scott Jordan
    In the 1980s, Sun Microsystems coined the trademark “The Network is the Computer” to herald the days of distributed computing. read more
  • Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Friday, January 28, 2011
    Technical Article
    Michael Lichtenauer, Stefanie Nickl, Konrad Hoetzenecker, Andreas Mangold, Andreas Mitterbauer, Stefan Hacker, Matthias Zimmermann, Hendrik Jan Ankersmit
    Phosphate-buffered saline (PBS), a buffer solution commonly used in many biological research fields, contains monobasic potassium phosphate, sodium chloride, and dibasic sodium phosphate. read more
  • Absorption and Emission Red Shift in Stained Cell and Tissue Samples

    Absorption and Emission Red Shift in Stained Cell and Tissue Samples

    Monday, May 05, 2008
    Technical Article
    Eugene Barash, Pavel A. Fomitchov, Robert Filkins, Mark Mayers, Anup Sood, Radislav A. Potyrailo, Hua Xia, Michael Montalto
    The design of fluorescence microscopes and selection of dyes are better served by the knowledge of environmental effects on dyes, whether they are in vitro or in vivo. read more
  • The LED Light Source: A Major Advance in Fluorescence Microscopy

    The LED Light Source: A Major Advance in Fluorescence Microscopy

    Wednesday, October 10, 2007
    Technical Article
    Becky Hohman
    Fluorescence microscopy requires an intense light source at the specific wavelength that will excite fluorescent dyes and proteins. read more
  • Microscopy is Moving On

    Microscopy is Moving On

    Friday, July 01, 2005
    Technical Article
    Aubrey Lambert
    The basis for observations has not really changed in all the time that lenses have been used to magnify objects. read more
  • Miniaturized FTIR for Maximized Productivity

    Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen, John S. Seelenbinder, Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more
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