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  • Electronic Pipetting: The Call for Innovation

    Thursday, February 27, 2014
    Application Note
    Paula Heimler
    Take a close look around most laboratories and you will find an old, barely used fixture. No one knows who ordered it or who it belongs to. It is yellowed, dusty, and top heavy, with a small keyboard ... read more

  • Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more

  • The Story of MALS

    Saturday, October 05, 2013
    Technical Article
    Philip J. Wyatt
    The concept of measuring light scattered from a solution at each of a plurality of angles simultaneously began in late 1976 in a very unlikely application. At that time, scientists from Science ... read more

  • A Sensitive and Selective GC/MS Method for Analyzing Persistent Organic Pollutants Using a Novel ...

    Friday, October 04, 2013
    Application Note
    Jody Dunstan
    Charge transfer chemical ionization (CI) was among the ionization types studied decades ago by researchers investigating fundamental Characteristics of chemical ionization. However, the technique was ... read more

  • Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays

    Friday, June 07, 2013
    Application Note
    Amedeo Cappione Masaharu Mabuchi David Briggs Timothy Nadler
    Many protein detection methods, including Western blotting, flow cytometry, ELISA, and immunohistochemistry, require the use of target-specific probes, such as antibodies, that are detected via two-... read more

  • Putting the “More” in Morphology: Part 1

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Segmentation, the ability to define the unique features in a region of interest, has always been the greatest challenge in image analysis and quantitation. A new suite of tools, available from ... read more

  • An Ultrasensitive Immunoassay Detection System for Biomarkers Utilizing Raman Scattering Methods

    Wednesday, October 31, 2012
    Technical Article
    Samar Kundu Charles Ginsburgh Sandra Lynch Neal Siegel
    Detection of low levels of biomarkers utilizing enzyme linked immunosorbent assay (ELISA) technology is demonstrated through the use of Raman scattering techniques and a convertible substrate for ... read more

  • Focus on Separation Science at Pittcon® 2012: Advances in Gas Chromatography

    Monday, May 07, 2012
    Technical Article
    Robert L. Stevenson, Ph.D.
    For gas chromatography (GC), the big news at Pittcon® 2012 was the absence of Agilent and PerkinElmer. This was a consequence of an overall downsizing caused by the “six-year effect” where the cycles ... read more

  • Food Safety Testing and New Technologies

    Friday, February 03, 2012
    Application Note
    Mukta M. Shukla
    Just as Alexander Fleming’s groundbreaking discoveries on penicillin ushered in a new era of antibacterial agents to extend human lifespans, it was the work of Louis Pasteur that helped introduce the ... read more

  • Focus on Columns and Consumables at Pittcon® 2011

    Tuesday, May 10, 2011
    Technical Article
    Robert L. Stevenson, Ph.D.
    Columns, chemicals, and consumables (CCCs) account for more than 30% of the chromatography market. read more

  • Effective UPLC Implementation

    Wednesday, April 06, 2011
    Technical Article
    Mark Dawson
    As the science of HPLC has evolved over the years, we have witnessed many changes to HPLC chemistry and instrumentation. read more

  • A New-Generation Microwave Digestion System

    Friday, January 28, 2011
    Application Note
    Carl Chan
    Since the laboratory microwave digestion system first became commercially available in the 1980s, sample preparation has become mainstream, and the preparation of samples for atomic spectroscopy has ... read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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