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  • The Story of MALS

    Saturday, October 05, 2013
    Technical Article
    Philip J. Wyatt
    The concept of measuring light scattered from a solution at each of a plurality of angles simultaneously began in late 1976 in a very unlikely application. At that time, scientists from Science ... read more
  • A Sensitive and Selective GC/MS Method for Analyzing Persistent Organic Pollutants Using a Novel ...

    Friday, October 04, 2013
    Application Note
    Jody Dunstan
    Charge transfer chemical ionization (CI) was among the ionization types studied decades ago by researchers investigating fundamental Characteristics of chemical ionization. However, the technique was ... read more
  • Focus on Separation Science at Pittcon® 2012: Advances in Gas Chromatography

    Monday, May 07, 2012
    Technical Article
    Robert L. Stevenson, Ph.D.
    For gas chromatography (GC), the big news at Pittcon® 2012 was the absence of Agilent and PerkinElmer. This was a consequence of an overall downsizing caused by the “six-year effect” where the cycles ... read more
  • Product Intelligence: Mass Spectrometers for Use in Clinical Diagnostics

    Friday, April 27, 2012
    Technical Article
    T. Keith Brock
    It is recommended that prospective purchasers of mass spectrometers for clinical diagnostics applications research key specifications in order to make an informed decision. This article points out ... read more
  • Food Safety Testing and New Technologies

    Friday, February 03, 2012
    Application Note
    Mukta M. Shukla
    Just as Alexander Fleming’s groundbreaking discoveries on penicillin ushered in a new era of antibacterial agents to extend human lifespans, it was the work of Louis Pasteur that helped introduce the ... read more
  • Focus on Columns and Consumables at Pittcon® 2011

    Tuesday, May 10, 2011
    Technical Article
    Robert L. Stevenson, Ph.D.
    Columns, chemicals, and consumables (CCCs) account for more than 30% of the chromatography market. read more
  • Effective UPLC Implementation

    Wednesday, April 06, 2011
    Technical Article
    Mark Dawson
    As the science of HPLC has evolved over the years, we have witnessed many changes to HPLC chemistry and instrumentation. read more
  • A New-Generation Microwave Digestion System

    Friday, January 28, 2011
    Application Note
    Carl Chan
    Since the laboratory microwave digestion system first became commercially available in the 1980s, sample preparation has become mainstream, and the preparation of samples for atomic spectroscopy has ... read more
  • Peptide De Novo Sequencing With MALDI TOF/TOF: A Simple Approach Using Sulfonation Chemistry

    Thursday, September 07, 2006
    Technical Article
    Paolo Conrotto Ulf Hellman
    One of the main focuses of the scientific community, now that major advances have been achieved in the comprehension of genome organization, has become the study of proteins, including their structure... read more
  • A System That Helps Scientists See Drugs in Tissue Samples

    Friday, July 01, 2005
    Application Note
    Mark Springer
    For drug developers, being able to see where a drug candidate is distributed in a targeted tissue helps them better assess the potential value of that compound as a pharmaceutical product. read more
  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more
  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more
  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more
  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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