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  • Urinary Drug Testing: Small Changes for Big Improvements in Sensitivity

    Tuesday, September 27, 2016
    Application Note
    Jenny Cybulski
    An oversight or mistake in drug testing can have dire consequences—a positive drug test can ruin the possibility of employment, turn an accident into a lawsuit, or cause a physician to discontinue ... read more

  • Automated Chromatographic Solid-Phase Extraction Using an Autosampler

    Thursday, September 01, 2016
    Application Note
    Mark Hayward Jonathan Ho Rick Youngblood Matthew T. Hardison Tom Moran Kim Gamble
    Solid-phase extraction (SPE) is a preferred tool for isolating target analytes from complex matrices because the availability of a diverse range of chromatographic sorbents enables targeted approaches... read more

  • Evaluation of an Automated Solid-Phase Extraction Method Using Positive Pressure

    Wednesday, April 08, 2015
    Application Note
    Heidi Fleischer Kerstin Thurow Ellen Vorberg Carolin Gallert Thomas Roddelkopf Steffen Junginger
    Investigations for the determination of drugs in real samples, while gaining in importance, are limited by time and sample throughput. In response to this, the authors developed an automated solid-... read more

  • Application of Porous Nano-Calcium Titanate in Preconcentration of Heavy Metals in Water

    Wednesday, October 15, 2014
    Application Note
    Dong Zhang Yan Li
    Heavy metal pollution in water has been a public concern for decades.Heavy metals, which include lead, cadmium, mercury, chromium, zinc, copper, and nickel, are highly toxic with hidden pollution, ... read more

  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more

  • How Solid-Phase Extraction Affects Challenges in Bioanalysis

    Wednesday, February 05, 2014
    Application Note
    Mike Oliver Tim Liddicoat Ken Meadows
    Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more

  • Pittcon 2013®: Developments in Liquid Chromatography

    Monday, May 13, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The first commercial liquid chromatograph was probably an amino acid analyzer. These ion exchange chromatographs were so specialized that they had almost no impact on chemical analysis outside of ... read more

  • Sample Prep for LC, GC, and SFC at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more

  • Product Intelligence: Solid Phase Extraction Systems

    Monday, February 25, 2013
    Technical Article
    Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more

  • Analyzing Volatile Organic Chemicals in Food: Emerging Trends and Recent Examples

    Thursday, February 14, 2013
    Technical Article
    David Barden
    The detection of volatile organic compounds (VOCs) is important for a variety of reasons, many of which stem either from the need to ensure that damaging chemicals are controlled or eliminated, or the... read more

  • New Instrumentation and Applications at HPLC 2012

    Friday, August 10, 2012
    Technical Article
    Robert L. Stevenson, Ph.D.
    A marketplace is usually dynamic, with a cross-current of disparate interests meeting to find mutual satisfaction. read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • Use of Microcoil Probes to Acquire More Sensitive NMR Spectral Data

    Tuesday, February 01, 2005
    Technical Article
    Peter Froehlich
    Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique that is commonly used to provide structural information as well as other chemical metrics such as sample composition ... read more
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