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  • High-Throughput Drug Screening of Multicellular Tumor Spheroids

    Tuesday, September 27, 2016
    Application Note
    Ana Maria P. Pardo Hannah J. Gitschier David H. Randle Terry Riss
    Three-dimensional (3-D) culture models are increasingly being used for drug discovery in oncology, as they better represent the complexity of the in vivo microenvironment of solid tumors. read more

  • Electrophoresis 2.0: Faster, Stronger, and More Reproducible

    Monday, August 04, 2014
    Application Note
    Ryan Jensen Stefan Lehr Anton Posch
    In 2010, researchers around the world were competing to finish the race to purify BRCA2, a protein whose mutant form is associated with more than 50% of hereditary breast cancer. But only one of ... read more

  • Interview With Richard Peters, President of NuAire, Inc.

    Tuesday, April 01, 2014
    Application Note
    Maria Stone
    Max D. Peters started the company back in 1971. He was an avionics engineer at Honeywell and he worked on satellites, aircraft, and other projects involving HEPA [high efficiency particle air] ... read more

  • The Scales of Scientific Justice in Translational Science: Data Reproducibility and Verifiable ...

    Tuesday, March 04, 2014
    Application Note
    Tristan Berto
    The traditional “scales of justice” represent truth and fairness. For the scientific community, the balance is between big data (terabytes of data across numerous databases) on one scale and ... read more

  • The Role of Synthetic DNA in Big DNA and Genetics Research

    Friday, August 02, 2013
    Technical Article
    Dan Gibson Hans Packer
    Synthetic biology is defined as the de novo design and construction of biological devices and systems, and as such is heavily reliant on the use of synthetic DNA. The size and sequence of potential ... read more

  • Product Intelligence: Thermal Cyclers: Behind the Technology

    Friday, June 28, 2013
    Technical Article
    Caitlin Smith
    Also referred to as thermocyclers, DNA amplifiers, or PCR machines, thermal cyclers are a vital part of the molecular biology laboratory. Many choices of thermal cycler are available, and this article... read more

  • Automated Cell Staining in Drug Discovery

    Tuesday, April 09, 2013
    Application Note
    Amy Yoder Li Liu
    Cell and molecular biology become more integral pieces of the modern drug discovery process on a seemingly daily basis. Monitoring the interaction of cells and internal cellular activity provides ... read more

  • Automated Assays and More at SLAS 2013 and HCA 2013

    Wednesday, February 06, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The second annual meeting of the Society for Laboratory Automation and Screening (SLAS 2013), held January 12–16, attracted 3800 scientists and engineers to the Gaylord Hotel in Orlando, FL for an ... read more

  • Light-Emitting Diodes: A New Solution for Fluorescence

    Saturday, October 01, 2011
    Technical Article
    Barbara Foster
    From the dramatic increase in new fluorophores to the proliferation of techniques like total internal reflection fluorescence (TIRF), photoactivated localization microscopy (PALM), and stochastic... read more

  • Automated ELISA Liquid Handling With a Combination Microplate Washer Dispenser

    Friday, April 17, 2009
    Application Note
    Paul Held Jason Greene
    Many biochemical assays involve the addition of different reagent fluids interrupted by delays or incubations to allow for a reaction to occur. read more

  • Fast Gravimetric Testing of Multichannel Pipets

    Monday, May 02, 2005
    Application Note
    Karl Heinz Lochner
    Piston pipets with air cushions have long been the standard equipment in many laboratories, especially in medical research and the life sciences for the transfer of liquids in the microliter range. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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