Also referred to as thermocyclers, DNA amplifiers, or PCR machines, thermal cyclers are a vital part of the molecular biology laboratory. Many choices of thermal cycler are available, and this article aims to simplify the selection process by outlining key considerations. These include: determining the size and type of thermal cycler required, the number of PCR reactions the thermal cycler will need to carry out, and whether a modular heating block system is necessary. The latest developments in thermal cyclers include the ability to analyze samples on site and WiFi capability.
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