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Quantitative Nanoparticle Analysis Based on Resistive Pulse Sensing
Friday, June 24, 2016
Application Note
Andrew N. Cleland Jean-Luc Fraikin Peter Meinhold Franklin Monzon
Nanoparticle analysis is becoming a central part of pharmaceutical development. read more
What Does Your Particle Size Data Mean?
Thursday, February 19, 2015
Application Note
Paul Kippax Deborah Huck-Jones
Laser diffraction is a mature technology with extensive capabilities. Highly automated and easy to use, modern laser diffraction systems efficiently meet the requirements for particle size data ... read more
Analytical Method Development in the Quality by Design Framework
Tuesday, December 16, 2014
Application Note
Torgny Fornstedt Dennis Åsberg Jörgen Samuelsson Anders Karlsson Krzysztof Kaczmarski
The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ... read more
Evolution of Wyatt Technology Corp.
Tuesday, May 06, 2014
Application Note
Robert L. Stevenson, Ph.D.
Over the last 56 years, Wyatt Technology Corp. (WTC), including the adaptation of innovations from its progenitor, Science Spectrum, has earned a reputation for developing and marketing instruments ... read more
The Story of MALS
Saturday, October 05, 2013
Technical Article
Philip J. Wyatt
The concept of measuring light scattered from a solution at each of a plurality of angles simultaneously began in late 1976 in a very unlikely application. At that time, scientists from Science ... read more
Product Intelligence: Particle Sizing Systems: Key to QC and Product Testing
Friday, September 20, 2013
Technical Article
Caitlin Smith
A host of particle sizing systems is available to measure a wide array of particle sizes. Fundamental checkpoints to consider before selecting a particle size analyzer include the range of particle ... read more
Characterizing Nanoparticles in Liquids: Protein Aggregation Studies
Monday, September 16, 2013
Application Note
Pauline Carnell Sarah Newell
Many patients’ lives have been improved with the use of monoclonal antibodies and recombinant proteins since their commercialization about 30 years ago. Work in the field of therapeutic proteins ... read more
Direct Improvement With Direct Dilution
Friday, August 09, 2013
Application Note
Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more
$Automated Refractive Index Calculations for Particle Size Analysis Using Laser Diffraction$
Automated Refractive Index Calculations for Particle Size Analysis Using Laser Diffraction
Monday, June 03, 2013
Technical Article
Mark Bumiller
Laser diffraction has been the most common particle size analysis technique for many years. The technique is fast, flexible, and easy to use for a wide variety of sample types. read more
R&D Informatics at Molecular Med Tri-Con 2013
Tuesday, February 26, 2013
Technical Article
Robert L. Stevenson, Ph.D.
Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in... read more
Drying of Problematic Purification Samples by Lyophilization in a Centrifugal Evaporator
Monday, June 13, 2011
Application Note
Induka Abeysena Rob Darrington
Lyophilization is often the preferred method of sample drying because a high level of dryness is achieved with low residual solvent levels, and because of the light, powdery, “fluffy” finish of the ... read more
Are You Attracted to Science? Attend Pittcon^®—The Magnet for Scientific Innovation
Tuesday, February 01, 2011
Technical Article
Penny. R Gardner
We are very excited for Pittcon^® 2011 to be back in Atlanta, GA, March 13–18, at the Georgia World Congress Center. read more
Understanding the Links Between Rheology and Particle Parameters
Wednesday, November 01, 2006
Technical Article
Steve Carrington Adrian Hill
The rheology of a suspension or dispersion relates directly to many parameters of commercial interest. read more
Sizing Particles
Tuesday, November 01, 2005
Technical Article
Michael Levin
Many methods and numerous instruments are available from recognized vendors to measure particle size. read more
Multicapillary Columns for Chromatography
Tuesday, March 01, 2005
Technical Article
Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more
Rapid Testing of Toxic Chemicals
Tuesday, March 01, 2005
Application Note
Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more
Miniaturized FTIR for Maximized Productivity
Tuesday, March 01, 2005
Application Note
Ken Fredeen John S. Seelenbinder Mark L. Norman
In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more
LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization
Tuesday, March 01, 2005
Technical Article
Wayne P. Duncan Patrick D. Perkins
Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more