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Title
Next-Generation Sequencing for Disease Biomarkers
Monday, December 15, 2014
Darren Lee
Next-generation sequencing (NGS) is beginning to provide powerful insights into genetic mutations and molecular networks underlying disease for a broad set of genes. NGS technologies promise to ...
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Analytical Method Development in the Quality by Design Framework
Tuesday, December 16, 2014
Torgny Fornstedt
Dennis Åsberg
Jörgen Samuelsson
Anders Karlsson
Krzysztof Kaczmarski
The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ...
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Electrochemical Determination of Acetaminophen Using Gold Nanoparticles–Multiwall Carbon Nanotubes Modified Glassy Carbon Electrode
Monday, December 15, 2014
Youyuan Peng
Zhifu Zheng
Since their discovery in 1991, carbon nanotubes (CNTs) have been extensively studied for use in emitting devices, energy storage, sensor field, and biological and biomedical applications.
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How Do You Evaluate “Flowability”? Buttermilk Ranch vs Blue Cheese
Monday, November 24, 2014
Robert G. McGregor
Eric Chiang
Stephanie Shepard
A common request from food manufacturers is to come up with a faster and more definitive test for flowability of salad dressings.
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Interview with Udit Batra, President and CEO, EMD Millipore
Tuesday, November 25, 2014
Emilia Raszkiewicz
ER: I am aware that there have been many exciting business developments within EMD Millipore in the past year, including your appointment as CEO and President. I trust that our discussion will give ...
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Role of Cetyltrimethylammonium Bromide in Preparing Porous In-TiO
2
Photocatalytic Material
Friday, January 02, 2015
Wenjie Zhang
Xiaobei Pei
Jinlei Chen
The application of TiO
2
as the main photocatalyst on degradation of organic pollutants has been widely investigated. Metal ion doping can retard recombination of photogenerated electron-hole pairs in ...
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LIMS and DNA Analysis in the Forensics Laboratory
Tuesday, February 17, 2015
Robin Gall
Laboratory information management systems (LIMS) are valuable tools in the forensics laboratory, streamlining the documentation and management of evidence including sample accession, extraction, ...
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Pure Water: The Most Essential Laboratory Element
Friday, January 16, 2015
Frank Gatzemeyer
Both vital and versatile, water is used in all laboratories, in preparing media, buffers and additives and for heating, cooling, cleaning and rinsing.
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The Importance of Monodisperse Silica in the Evolution of UHPLC and HPLC Column Performance
Tuesday, March 10, 2015
Richard A. Henry
Paul Ross
William R. Betz
Gaurang Parmar
Wayne K. Way
There is growing interest in the use of monodisperse particle-size distribution or PSD (here defined as having 10% RSD or less) to prepare modern HPLC columns because good correlation has been ...
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What Does Your Particle Size Data Mean?
Thursday, February 19, 2015
Paul Kippax
Deborah Huck-Jones
Laser diffraction is a mature technology with extensive capabilities. Highly automated and easy to use, modern laser diffraction systems efficiently meet the requirements for particle size data ...
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Use of Microcalorimetry to Study Protein Stability
Monday, February 16, 2015
Rémi André
Link Brown
Differential scanning calorimetry (DSC) is used in the pharmaceutical, polymer and biotechnology industries to study the effect of temperature on a variety of solids or liquids, including those that ...
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High-Throughput Tools for Optimizing Drug Nanosuspensions
Thursday, February 19, 2015
Dennis H. Leung
Timothy Rhodes
Annette Bak
Inadequate absorption and bioavailability often make it difficult to deliver the drug to the target in vivo and pose significant challenges to the discovery and development of new drugs. A number of ...
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Evaluation of an Automated Solid-Phase Extraction Method Using Positive Pressure
Wednesday, April 08, 2015
Heidi Fleischer
Kerstin Thurow
Ellen Vorberg
Carolin Gallert
Thomas Roddelkopf
Steffen Junginger
Investigations for the determination of drugs in real samples, while gaining in importance, are limited by time and sample throughput. In response to this, the authors developed an automated solid-...
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Detecting Trace-Level Pyrethroid Insecticides in Sewage and Ocean Sediments With GC-MS/MS
Wednesday, April 01, 2015
Joe Anacleto
As the use of pyrethroid insecticides continues to increase in the United States, it is becoming increasingly important to monitor levels of the compounds in environmental waters, river and ocean ...
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Simplified Bioanalytical Sample Preparation
Wednesday, April 08, 2015
Erica Pike
The complexity of biological samples can pose challenges to downstream analysis in the pharmaceutical industry. Bioanalytical and drug metabolism and pharmacokinetics (DMPK) groups often work with ...
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Determination of Olive Oil Adulteration With 60-MHz Benchtop NMR Spectrometry
Wednesday, April 01, 2015
Susanne D. Riegel
While the health benefits of extra virgin olive oil (EVOO) are well documented, the purity of any specific batch remains highly debatable. The great demand for EVOO, paired with the relatively high...
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Depth Profiling Trimethylaluminum-Modified PET Fibers by Nanoscale Infrared Spectroscopy
Wednesday, April 01, 2015
Curtis Marcott
Michael Lo
Eoghan Dillon
Halil I. Akyildiz
Jesse S. Jur
The development of flexible electronic devices for use as biosensors, optics or photovoltaic applications is a promising research area. Many common, inexpensive polymers can be processed in large ...
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Validation of a Magnetic Bead Mixer on an Automated Next-Generation Sequencing Library Preparation System
Tuesday, April 07, 2015
Sikander Gill
Rajwant Gill
Nick Bandy
Dong Liang
Reduced costs and higher throughput have made next-generation sequencing (NGS) more accessible to users in such diverse fields as diagnostics, infectious disease, food safety and public health. NGS ...
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Portable Raman Microscopy: Laboratory-Quality Results Measured Anywhere
Wednesday, April 22, 2015
Barbara Foster
While handheld portable Raman is now well established, until recently, microRaman had yet to make the leap out of the laboratory and into the world at large. To meet that challenge, BioTools (Jupiter...
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Identification of Microplastics in the Marine Environment by Raman Microspectroscopy and Imaging
Tuesday, April 28, 2015
Dieter Fischer
Andrea Kaeppler
Klaus-Jochen Eichhorn
Each year, 5–13 million tons of plastic debris enter the oceans. The main reason for this is the inappropriate disposal of waste from industrialized nations.
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