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Statistics in Analytical Chemistry: Part 35—Reporting Data and Significant Digits
Thursday, August 20, 2009
David Coleman Lynn Vanatta
"In almost all cases when dealing with a limit of detection or limit of determination, the primary purpose of determining that limit is to stay away from it.” read more
Statistics in Analytical Chemistry: Part 36—Significant Digits (Concluded)
Tuesday, January 26, 2010
David Coleman Lynn Vanatta
The previous article (Part 35, American Laboratory, Aug 2009) introduced the concept of significant digits, pointing out that a statistically sound treatment will: 1) result in a formula that depends ... read more
Statistics in Analytical Chemistry: Part 37—Deviations, Errors, and Intervals (Oh My!)
Thursday, February 18, 2010
David Coleman Lynn Vanatta
For the past seven years, this column has chiefly presented basic material related to a single theme: regression analysis of analytical data and the associated uncertainty. read more
Statistics in Analytical Chemistry: Part 38—Inexact Replicates
Tuesday, May 18, 2010
David Coleman Lynn Vanatta
In this series of articles, all of the regression discussions to date have assumed that the replicate preparations of a given concentration have been exact. read more
Statistics in Analytical Chemistry: Part 39—Inexact Replicates: Example
Thursday, August 12, 2010
David Coleman Lynn Vanatta
The previous installment (Part 38, American Laboratory, May 2010) outlined the regression-diagnostic steps needed when replicates are not exact. read more
Statistics in Analytical Chemistry: Part 40—Blanks
Friday, October 29, 2010
David Coleman Lynn Vanatta
There are indeed statistical issues related to blanks. To set the stage, a discussion of the concept itself will be helpful. read more
Characterization of a Cell Invasion Assay for High-Content Screening Using a Laser Microplate Cytometer
Tuesday, February 01, 2011
Keren Hulkower Joanne Franklin Paul Wylie David Onley
Cancer invasion from a primary tumor site is one of the critical factors in disease prognosis, and together with metastasis is the major cause of morbidity and mortality. read more
Highlights from the 21st Annual International Light Scattering Colloquium
Tuesday, February 01, 2011
Robert L. Stevenson, Ph.D.
The new world of very large molecules requires advanced analytics, particularly for structures with a molar mass larger than one million daltons extending up to particles with diameters of 1000 nm. read more
Are You Attracted to Science? Attend Pittcon^®—The Magnet for Scientific Innovation
Tuesday, February 01, 2011
Penny. R Gardner
We are very excited for Pittcon^® 2011 to be back in Atlanta, GA, March 13–18, at the Georgia World Congress Center. read more
Multistranded, Alternative, and Helical Transitional DNA and RNA Microarrays: The Next Generation
Thursday, March 10, 2011
Claude E. Gagna W. Clark Lambert
The genetic information used in the growth and operation of living organisms is contained in DNA, a specific type of nucleic acid molecule. read more
Statistics in Analytical Chemistry: Part 15—Calibration Example 5
Tuesday, February 01, 2005
David Coleman Lynn Vanatta
This real-world example of calibration diagnostics involves the ion-chromatographic behavior of phosphoric acid; phosphate is the actual analyte form that is measured by the instrument. read more
Statistics in Analytical Chemistry: Part 16—Calibration Example 5 (Concluded)
Sunday, May 01, 2005
David Coleman Lynn Vanatta
In the previous article (American Laboratory, Feb 2005), calibration data were diagnosed for a study involving phosphate. read more
Statistics in Analytical Chemistry: Part 17—Calibration Example 6
Monday, August 01, 2005
David Coleman Lynn Vanatta
This installment will present the sixth and last in this series of calibration examples. read more
Bridging the Gap Between Research and IT
Thursday, March 10, 2011
Matt Hahn
At the heart of every scientific research and development effort is a significant amount of data. read more
Statistics in Analytical Chemistry: Part 18—Calibration Example 6 (Concluded)
Thursday, September 01, 2005
David Coleman Lynn Vanatta
In the previous article (American Laboratory Aug 2005), borate data were presented. No single model was found to be adequate. read more
Statistics in Analytical Chemistry: Part 19—Internal Standards
Thursday, December 01, 2005
David Coleman Lynn Vanatta
The previous several articles have dealt with calibrationstudy design and calibration-diagnostic procedures. read more
Statistics in Analytical Chemistry: Part 20—Recovery Curves
Wednesday, February 01, 2006
David Coleman Lynn Vanatta
In Part 19 of this series (American Laboratory Dec 2005), the use of an internal standard (IS) was discussed and an example was given. read more
Optimal Baseline Correction for Multivariate Calibration Using Open-Source Software
Thursday, March 10, 2011
Kristian Hovde Liland Trygve Almøy Bjørn-Helge Mevik
Baseline estimation and correction is critical for many types of spectral data. read more
Statistics in Analytical Chemistry: Part 21—Recovery Curves and Internal Standards (Concluded)
Saturday, April 01, 2006
David Coleman Lynn Vanatta
The previous two installments have discussed the issue of nonideal recovery, a problem that occurs in many analytical methods. read more
Statistics in Analytical Chemistry: Part 22—Lack-of-Fit Details
Thursday, June 01, 2006
David Coleman Lynn Vanatta
Because of popular demand from readers, this installment will discuss the principles and calculations that underlie the lack-of-fit (LOF) test. read more

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