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Celebrating 25 Years of Inductively Coupled Plasma-Mass Spectrometry
Friday, September 26, 2008
Jeanely Hunt, MS, MBA
2008 marked the 25th anniversary of inductively coupled plasma-mass spectrometry (ICP-MS). read more
Fritless Chromatographic Microfluidic-Based Columns for Chemical Separations
Monday, October 27, 2008
Frank A. Gomez Attila Gaspar Shima Baghdachi Mark Goldberg Schetema Stevens Jaime Torres Marisol Salgado
The development of microfluidic chips and devices offers a number of advantages over conventional analytical techniques, including small sample volume requirements, portability, fast sampling times, ... read more
Unlocking the Secrets of Automation in the Pharmaceutical Laboratory
Monday, October 27, 2008
Abe Kassis Tarun Patel Kevin Bynum Roy Paul
A brief discussion about dissolution is important to understand the relevance of automation to this field. read more
The Helium Ion Microscope: The Next Stage in Nanoscale Imaging
Monday, November 24, 2008
Larry Scipioni Mohan Ananth John Notte
The helium ion microscope is being proven to offer solutions for imaging at the nanoscale. read more
The Role of Analytical Instrumentation in the Life Sciences
Saturday, November 01, 2008
Robert L. Stevenson, Ph.D. C. David Carr
Historically, the life sciences have been qualitative in nature, seeking to identify but seldom understand quantitatively. read more
Measurement of Viscosity in a Vertical Falling Ball Viscometer
Monday, October 27, 2008
Ping Yuan Ben-Yuan Lin
A number of methods are used to measure the viscosity of fluids. read more
What is “Hot” in Column Technologies for Liquid Chromatography?
Thursday, December 04, 2008
Frantisek Svec
It has been just over 100 years since Russian botanist Mikhail Semionovich Tswett invented the separation technique that he named chromatography. read more
Making Single-Molecule Sequencing a Reality
Friday, December 05, 2008
Avak Kahvejian Steve Kellett
The quest to directly sequence individual strands of DNA has challenged genomic technologists for decades. read more
Desktop Biological Nanopatterning Using Dip-Pen Nanolithography
Friday, December 05, 2008
Jason Haaheim Omkar A. Nafday
The ability to control the size and shape of deposited chemical structures on the nanoscale opens up new and exciting possibilities for the development of devices for use in the electronic, life ... read more
An Immunoaffinity Capillary Electrophoresis Biomarker Analyzer for Use in Toxicoproteomics Research
Friday, December 05, 2008
Norberto A. Guzman
The slow pace of discovery of new protein biomarkers of toxicity or “toxicity signature protein/peptides” is partially due to the lack of high-throughput and high-sensitivity biomarker devices. read more
WS-CRDS: Precision Trace Gas Analysis and Simplified Stable Isotope Measurements
Friday, December 05, 2008
Eric R. Crosson
Wavelength-scanned cavity ring-down spectroscopy (WSCRDS) is fast gaining worldwide acceptance as a superior tool for trace gas analysis, because it combines operational simplicity and portability ... read more
Optimizing Low-Volume Automated Liquid Handling
Friday, January 01, 2010
Brian C. Hewson
Liquid handling as a whole, regardless of throughput, demands precision and accuracy to minimize experimental variation and produce reliable experimental data. read more
A Cell Culture CO2 Incubator Using Hydrogen Peroxide Sterilization
Friday, January 01, 2010
Deepak Mistry Hiroki Busujima Matt Siebert
The use of a hydrogen peroxide vapor (H2O2) atomizer in situ to decontaminate a cell culture CO2 incubator without the use of heat sterilization offers significant advantages in routine clinical and ... read more
Characterizing Protein–Protein Interactions Via Static Light Scattering: Inhibition Kinetics and Dissociation
Tuesday, February 02, 2010
Dan Some Amy Hanlon
Quantification of the kinetic rates of protein association, dissociation, and aggregation is an essential factor in understanding and ultimately manipulating these phenomena. A variety of measurement ... read more
Automated Sample Preparation to Resolve Homogenizing Bottlenecks
Tuesday, March 23, 2010
Karl Jahn
Shorter product life cycles and rapidly expanding data processing capability are driving businesses to seek ever-faster methods of development. read more
Simplified Detection of Proteins in the Picogram and Femtogram Range
Monday, March 01, 2010
Paula Maia Helen M.M. Webster Seth Harkins
Western blotting is one of the most commonly used applications in protein research. read more
Statistics in Analytical Chemistry: Part 41—Blanks (Concluded)
Friday, January 28, 2011
David Coleman Lynn Vanatta
The previous article (American Laboratory, Oct 2010) left off with two interesting questions: 1) How does an analyst decide whether a positive response for a blank is low enough to be ignored? and 2) ... read more
A Practical Guide to Publishing RT-qPCR Data That Conform to the MIQE Guidelines
Tuesday, March 23, 2010
Sean Taylor
Real-time quantitative PCR (qPCR) has become a definitive technique for quantitating differences in gene expression levels between samples. read more
The Role of the Anaerobic Chamber in Microbiology Today
Wednesday, May 26, 2010
Brian Coy
The anaerobic chamber, developed more than 40 years ago for microbiologic use, has evolved with operators’ needs and remains a significant tool for research and other applications worldwide. read more
Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells
Friday, January 28, 2011
Michael Lichtenauer Stefanie Nickl Konrad Hoetzenecker Andreas Mangold Andreas Mitterbauer Stefan Hacker Matthias Zimmermann Hendrik Jan Ankersmit
Phosphate-buffered saline (PBS), a buffer solution commonly used in many biological research fields, contains monobasic potassium phosphate, sodium chloride, and dibasic sodium phosphate. read more