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Centrifuge Rotor Material Evolution: Advances in Rotor Design Using Composite Materials
Wednesday, May 26, 2010
Sheila Piramoon
Centrifuges are common and important tools for the laboratory. Choosing the right rotor system for each centrifuge can maximize the equipment’s performance and longevity.
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New Technologies to Further Genomics in Clinical Research
Saturday, May 01, 2010
Peer Staehler
Rapidly evolving technologies in genomic research and the accessibility of genomic data within recent years have significantly changed biomedical research.
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High-Capacity 1-mm-i.d. Polymer Monoliths for Fast Protein Separations
Friday, January 28, 2011
Christopher Pohl
Srinivasa Rao
Kelly J. Flook
Charanjit Saini
Maria Rey
Andy Woodruff
Jim Thayer
Yury Agroskin
Over the last decade, monolith technology has progressed from a promising approach conceived by Fréchet, Švec, Huber, and others to a well-developed separation tool.
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2-D in a Day: A Two-Dimensional Gel Electrophoresis Work Flow Completed in Under Five Hours
Monday, July 26, 2010
Gary B. Smejkal
Darren J. Bauer
While O’Farrell first described two-dimensional electrophoresis (2DE) of proteins 35 years ago, it remains one of the most widely used tools in proteomics today.
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The Importance of Optimizing the DNA Purification Protocol in Magnetic Particle-Based Systems
Monday, July 26, 2010
Marika Suomalainen
Sini Suomalainen
Virpi Puro
Vuokko Kytoniemi
Arja Lamberg
Magnetic particle-based techniques are widely used in many diverse biological applications, offering a relatively inexpensive technology and subjecting samples to very little mechanical stress.
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Highlights From the 22nd International Ion Chromatography Symposium (IICS 2010)
Friday, January 07, 2011
Robert L. Stevenson, Ph.D.
Many wonder if the time has come to merge ion chromatography (IC) with HPLC.
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The Road to Better Cell Culture Outcomes
Wednesday, September 01, 2010
David Craig
In an environment literally covered in microorganisms, keeping cell cultures contaminant free is both challenging and essential.
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Biological Imaging: What More Can It Provide?
Thursday, September 30, 2010
Larry Scipioni
Shawn McVey
Lewis Stern
The physicist Richard Feynman famously said in reference to (what is now called) nanotechnology, that “there is plenty of room at the bottom.”
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A Novel Performance Test for Outlet Check Valve Function in HPLC Pumps
Tuesday, September 28, 2010
Eduard Rogatsky
Matthew Gallitto
Daniel T. Stein
Check valves are a vital mechanical component of HPLC pump hardware. A detailed description of check valve function and hardware designs is given in Ref. 1.
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A Microfluidics-Based Droplet Plate Reader for Nucleic Acid and Protein Quantification
Wednesday, September 01, 2010
Tony Montoye
Life science laboratories are gradually moving toward automated liquid handling to achieve cost reduction, productivity increases, and improved data consistency and quality.
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The Interaction Between Gemini Surfactant and Bovine Serum Albumin
Thursday, September 30, 2010
Mao Peng
Hui Wu
Lijiao Sheng
Gongwu Song
Jiangang Zhou
In recent years, Gemini surfactants have emerged as promising surface active agents.
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A Generic Method for the Analysis of Residual Solvents in Pharmaceuticals Using Static Headspace-GC-FID-MS
Tuesday, February 01, 2011
Frank David
Pat Sandra
Karine Jacq
Matthew S. Klee
The determination of residual solvents (RS), formerly called organic volatile impurities (OVI), in pharmaceutical products is probably the most important application of gas chromatography in ...
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Staistics in Analytical Chemistry: Part 28—Statistically Derived Detection Limits
Friday, December 28, 2007
David Coleman
Lynn Vanatta
In the previous article (Part 27, American Laboratory, Sept 2007), the world of detection was shown to revolve around three variables: 1) the detection limit, 2) the probability of false positives, a,...
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Statistics in Analytical Chemistry: Part 29—Statistically Derived Detection Limits (continued)
Thursday, February 28, 2008
David Coleman
Lynn Vanatta
Part 28 (American Laboratory, Nov/Dec 2007) laid the framework for discussing detection limits. The relationship among the detection limit (DL), the probability of false positives (a), and the ...
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Statistics in Analytical Chemistry: Part 30—Statistically Derived Detection Limits (Concluded)
Thursday, July 10, 2008
David Coleman
Lynn Vanatta
In Part 29 (American Laboratory, Feb 2008), Hubaux-Vos detection limits (H-V DLs) were explained and an illustration was given.
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Determination of Enantiomeric Purity of a-Bromobutyric Acid by HPLC Combined With Pre-Column Derivatization
Tuesday, February 01, 2011
Jia Luo
Quanyi Wang
Yiwen Zhang
Hang Song
Shun Yao
As a common intermediate in the synthesis of numerous pharmaceuticals, a-bromobutyric acid displays chirality at the carbon bound to the bromine.
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Statistics in Analytical Chemistry: Part 31—Receiver Operating Characteristic (ROC) Curves: Equations
Friday, September 26, 2008
David Coleman
Lynn Vanatta
Please do not despair! This article is not a series of formulas to be memorized.
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Statistics in Analytical Chemistry: Part 32—Detection Limits Via 3-Sigma
Friday, December 05, 2008
David Coleman
Lynn Vanatta
As was mentioned in the first article on detection limits (DLs) (Part 26, American Laboratory, June/July 2007), many formulas exist for calculating these values.
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Statistics in Analytical Chemistry: Part 33—Detection Limits via 3-Sigma (Concluded)
Friday, March 20, 2009
David Coleman
Lynn Vanatta
In the last installment (Part 32, American Laboratory, Nov/Dec 2008) of this series, three detection limits (DLs) were calculated (via the 3-Sigma [3s] approach, where a is set to be 0.01) for a ...
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Statistics in Analytical Chemistry: Part 34—Detection-Limit Summary
Thursday, May 28, 2009
David Coleman
Lynn Vanatta
The subject of detection limits (DLs) is a controversial one, generating many questions and almost endless debate.
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