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  • Automated Botulinum Neurotoxin Detection

    Automated Botulinum Neurotoxin Detection

    Monday, February 25, 2013
    Technical Article
    Karine Bagramyan, Aneela Reddy, Dobrin Nedelkov, Markus Kalkum
    Botulinum neurotoxin (BoNT) is undoubtedly the most potent biological toxin known. Intravenously injected it could paralyze and kill a human being at a dose of just 1.2 ng BoNT per kg body weight. read more
  • Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Friday, February 08, 2013
    Technical Article
    Robert L. Stevenson
    Most commonly, laboratory automation involves a few hundred wells run for a specific purpose. SLAS 2013, the meeting of the Society for Laboratory Automation and Screening, was held at the Gaylord ... read more
  • Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Thursday, January 17, 2013
    Application Note
    Robert L. Stevenson
    Expanded bed adsorption (EBA) was introduced in 1999 with adsorbents that were used for pressure-driven packed beds. These had densities in the range of 1.1–1.5 g/mL, which was not much higher than ... read more
  • Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Monday, December 24, 2012
    Technical Article
    Laurent Baron, Bobby Chavli, Lois Tack, Annette Summers
    For years, forensic laboratories in the U.S. have struggled to reduce DNA sample processing backlogs and human errors, both of which hinder timely and reliable criminal convictions. read more
  • Optimizing HPLC Sample Preparation

    Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more
  • Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Friday, January 28, 2011
    Technical Article
    Michael Lichtenauer, Stefanie Nickl, Konrad Hoetzenecker, Andreas Mangold, Andreas Mitterbauer, Stefan Hacker, Matthias Zimmermann, Hendrik Jan Ankersmit
    Phosphate-buffered saline (PBS), a buffer solution commonly used in many biological research fields, contains monobasic potassium phosphate, sodium chloride, and dibasic sodium phosphate. read more
  • Calorimetry: Getting the Winning Combination

    Calorimetry: Getting the Winning Combination

    Wednesday, July 18, 2007
    Technical Article
    Ed Sullivan
    Ultrasensitive calorimetric instruments for measuring very small heats of reaction at constant temperature (isothermal titration calorimetry [ITC]) and small heat effects induced by temperature (... read more
  • Stability of Salicylic Acid and Magnesium Stearate by DSC

    Stability of Salicylic Acid and Magnesium Stearate by DSC

    Saturday, April 01, 2006
    Application Note
    Steven Sauerbrunn, Lloyd MacPherson
    The first step in developing effective pharmaceutical formulations is the discovery of the active agent. read more
  • A Multifrequency Temperature-Modulated Technique For DSC

    A Multifrequency Temperature-Modulated Technique For DSC

    Sunday, January 01, 2006
    Application Note
    Markus Schubnell, Christoph Heitz, Thomas Hütter, Steven Sauerbrunn, Juergen E.K. Schawe
    In conventional differential scanning calorimetry (DSC), a sample is subjected to a temperature program with a constant heating rate. As a result, the DSC instrument delivers an output signal, which, ... read more
  • A High-Sensitivity Sensor for DSC

    A High-Sensitivity Sensor for DSC

    Friday, August 05, 2005
    Application Note
    Rudolf Riesen, Blaine Weddle
    A dramatic increase in sensitivity at low signal noise without a significant loss in signal resolution has been achieved with the HSS7 high-sensitivity sensor. read more
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