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  • Protein Aggregation at PepTalk 2014

    Monday, March 31, 2014
    Technical Article
    Robert L. Stevenson, Ph.D.
    Quantitative analysis of subvisible particles is an important unsolved problem, as discussed in the Particle Analysis track of PepTalk 2014, held January 12–17 at the Renaissance Hotel and Palm ... read more

  • Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more

  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more

  • High-Content Analysis (HCA 2013): 3-D Reduces the Gap Between In Vitro and In Vivo

    Tuesday, February 05, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The 10th High-Content Analysis meeting attracted about 300 scientists to San Francisco’s Fairmont Hotel (January 8–11, 2013). A Venn diagram of attendees would certainly include overlapping circles ... read more

  • Diagnostic, Prognostic, and Predictive: The Dynamic Role of Molecular Technology in Personalized ...

    Tuesday, January 10, 2012
    Technical Article
    T. Keith Brock
    The expected growth of molecular techniques over the next 10 years will have a profound impact on clinical decision-making. read more

  • Laser Diffraction: A Firm Foundation for Particle Characterization

    Tuesday, August 02, 2011
    Technical Article
    Paul Kippax Carl Levoguer
    For manufacturers of solid and/or particulate products, particle size is frequently a critical parameter, and is one of the principal variables routinely used to characterize their materials. read more

  • Particle Image Analysis: Microscopy Takes a Technological Leap Forward

    Friday, August 29, 2008
    Technical Article
    Graham Rideal
    Electrical sensing zones, low-angle laser light scattering, field flow fractionation, photon correlation spectroscopy, hydrodynamic chromatography, and laser obscuration time are just some of the ... read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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