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  • High-Throughput Drug Screening of Multicellular Tumor Spheroids

    Tuesday, September 27, 2016
    Application Note
    Ana Maria P. Pardo Hannah J. Gitschier David H. Randle Terry Riss
    Three-dimensional (3-D) culture models are increasingly being used for drug discovery in oncology, as they better represent the complexity of the in vivo microenvironment of solid tumors. read more

  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more

  • How Solid-Phase Extraction Affects Challenges in Bioanalysis

    Wednesday, February 05, 2014
    Application Note
    Mike Oliver Tim Liddicoat Ken Meadows
    Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more

  • Product Intelligence: Solid Phase Extraction Systems

    Monday, February 25, 2013
    Technical Article
    Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more

  • Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more

  • High-Precision, High-Sensitivity Measurements of Lead and Cadmium in Honey by GFAAS

    Monday, March 01, 2010
    Application Note
    Zhi-Gang Ouyang Zhong-Lan Chen Ying Wu
    Honey is a natural substance produced in honeycombs by honeybees under special conditions. For centuries, honey has often been referred to as nature’s medicine. It is known to help heal bronchial ... read more

  • A New Approach to Atomic Force Microscopy for Nanometrology Applications

    Friday, April 01, 2005
    Application Note
    Paul West Zhiqiang Peng Natalia Starostina
    Since the invention of the atomic force microscope (AFM), the use of high-resolution topographic images has become the standard in microscopy and surface science publications. read more

  • Use of New Scanning Technology to Elucidate Ion Channel Mobility

    Friday, April 01, 2005
    Application Note
    Angela Goodacre Kristen M.S. O’Connell Michael M. Tamkun
    Fluorescent chromophores fused to specific proteins have greatly increased our ability to image dynamic events within the living cell. read more
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