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  • Protein Aggregation at PepTalk 2014

    Monday, March 31, 2014
    Technical Article
    Robert L. Stevenson, Ph.D.
    Quantitative analysis of subvisible particles is an important unsolved problem, as discussed in the Particle Analysis track of PepTalk 2014, held January 12–17 at the Renaissance Hotel and Palm ... read more
  • Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more
  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more
  • High-Content Analysis (HCA 2013): 3-D Reduces the Gap Between In Vitro and In Vivo

    Tuesday, February 05, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The 10th High-Content Analysis meeting attracted about 300 scientists to San Francisco’s Fairmont Hotel (January 8–11, 2013). A Venn diagram of attendees would certainly include overlapping circles ... read more
  • Diagnostic, Prognostic, and Predictive: The Dynamic Role of Molecular Technology in Personalized ...

    Tuesday, January 10, 2012
    Technical Article
    T. Keith Brock
    The expected growth of molecular techniques over the next 10 years will have a profound impact on clinical decision-making. read more
  • Applications of PTR-MS in Medicine and Biotechnology

    Tuesday, June 14, 2011
    Technical Article
    Wolfgang Singer Jens Herbig Rene Gutmann Klaus Winkler Ingrid Kohl Armin Hansel
    Proton transfer reaction-mass spectrometry (PTR-MS) is a well-established analytical tool for the measurement of volatile organic compounds (VOCs), and offers real-time detection and ... read more
  • Accurate Determination of Amino Acids in High-Carbohydrate-Containing Samples

    Sunday, October 01, 2006
    Technical Article
    Valoran P. Hanko Jeffrey S. Rohrer
    In a high-sensitivity amino acid analysis (AAA) technique that does not require sample derivatization, both amino acids and carbohydrates are separated by high-performance anion-exchange ... read more
  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more
  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more
  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more
  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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