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  • Integrating Microscopy Into the Analytical Scheme: A Pittcon® 2014 Microscopy Review

    Monday, February 24, 2014
    Technical Article
    Barbara Foster
    Microscopy is often overlooked at Pittcon®, yet of the 12,000+ scientists who attend, approximately 30% use microscopy in some form (according to ongoing research from The Microscopy & Imaging Place, ... read more

  • Light-Emitting Diodes: A New Solution for Fluorescence

    Saturday, October 01, 2011
    Technical Article
    Barbara Foster
    From the dramatic increase in new fluorophores to the proliferation of techniques like total internal reflection fluorescence (TIRF), photoactivated localization microscopy (PALM), and stochastic... read more

  • Increased IEF Throughput Using a Dual-Electrode Assembly

    Tuesday, August 02, 2011
    Application Note
    Gary B. Smejkal Darren J. Bauer
    An isoelectric focusing (IEF) apparatus capable of operating at 12,000 V maximum voltage enables isoelectric focusing of proteins in immobilized pH gradients (IPGs) to be completed in less than 3 hr. read more

  • Characterization of a Cell Invasion Assay for High-Content Screening Using a Laser Microplate ...

    Tuesday, February 01, 2011
    Technical Article
    Keren Hulkower Joanne Franklin Paul Wylie David Onley
    Cancer invasion from a primary tumor site is one of the critical factors in disease prognosis, and together with metastasis is the major cause of morbidity and mortality. read more

  • Absorption and Emission Red Shift in Stained Cell and Tissue Samples

    Monday, May 05, 2008
    Technical Article
    Eugene Barash Pavel A. Fomitchov Robert Filkins Mark Mayers Anup Sood Radislav A. Potyrailo Hua Xia Michael Montalto
    The design of fluorescence microscopes and selection of dyes are better served by the knowledge of environmental effects on dyes, whether they are in vitro or in vivo. read more

  • Microscopy is Moving On

    Friday, July 01, 2005
    Technical Article
    Aubrey Lambert
    The basis for observations has not really changed in all the time that lenses have been used to magnify objects. read more

  • Use of New Scanning Technology to Elucidate Ion Channel Mobility

    Friday, April 01, 2005
    Application Note
    Angela Goodacre Kristen M.S. O’Connell Michael M. Tamkun
    Fluorescent chromophores fused to specific proteins have greatly increased our ability to image dynamic events within the living cell. read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more
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