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  • Single-Cell RNA Detection to Identify Cell Subpopulations in Heterogeneous Mixtures

    Single-Cell RNA Detection to Identify Cell Subpopulations in Heterogeneous Mixtures

    Tuesday, March 25, 2014
    Application Note
    Don Weldon, Victor Koong, Alex Ko, Yuko Williams, Laura White
    Traditional RNA detection methods, which analyze RNA levels in lysed, permeabilized, or fixed cell samples, make it challenging to understand the role of one gene in the context of a tissue, organ, or... read more
  • Flow Cytometry Applied to Plant Reproductive Biology

    Flow Cytometry Applied to Plant Reproductive Biology

    Thursday, November 07, 2013
    Application Note
    Diego H. Hojsgaard, Elmar Herbig
    Understanding how biodiversity is distributed in nature and how it is impacted by human activities has become crucial for nature conservation. read more
  • Putting the “More” in Morphology: Part 1

    Putting the “More” in Morphology: Part 1

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Segmentation, the ability to define the unique features in a region of interest, has always been the greatest challenge in image analysis and quantitation. A new suite of tools, available from ... read more
  • Product Intelligence: Considerations for Selecting Flow Cytometers

    Product Intelligence: Considerations for Selecting Flow Cytometers

    Monday, February 25, 2013
    Technical Article
    Caitlin Smith
    Apoptosis, cell proliferation, cell cycle regulation, and immunophenotyping are some of the areas in which flow cytometers find application. Researchers have many options to consider when shopping for... read more
  • Automated Botulinum Neurotoxin Detection

    Automated Botulinum Neurotoxin Detection

    Monday, February 25, 2013
    Technical Article
    Karine Bagramyan, Aneela Reddy, Dobrin Nedelkov, Markus Kalkum
    Botulinum neurotoxin (BoNT) is undoubtedly the most potent biological toxin known. Intravenously injected it could paralyze and kill a human being at a dose of just 1.2 ng BoNT per kg body weight. read more
  • Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Friday, February 08, 2013
    Technical Article
    Robert L. Stevenson
    Most commonly, laboratory automation involves a few hundred wells run for a specific purpose. SLAS 2013, the meeting of the Society for Laboratory Automation and Screening, was held at the Gaylord ... read more
  • Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Thursday, January 17, 2013
    Application Note
    Robert L. Stevenson
    Expanded bed adsorption (EBA) was introduced in 1999 with adsorbents that were used for pressure-driven packed beds. These had densities in the range of 1.1–1.5 g/mL, which was not much higher than ... read more
  • Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Monday, December 24, 2012
    Technical Article
    Laurent Baron, Bobby Chavli, Lois Tack, Annette Summers
    For years, forensic laboratories in the U.S. have struggled to reduce DNA sample processing backlogs and human errors, both of which hinder timely and reliable criminal convictions. read more
  • Optimizing HPLC Sample Preparation

    Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more
  • Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Friday, January 28, 2011
    Technical Article
    Michael Lichtenauer, Stefanie Nickl, Konrad Hoetzenecker, Andreas Mangold, Andreas Mitterbauer, Stefan Hacker, Matthias Zimmermann, Hendrik Jan Ankersmit
    Phosphate-buffered saline (PBS), a buffer solution commonly used in many biological research fields, contains monobasic potassium phosphate, sodium chloride, and dibasic sodium phosphate. read more
  • Detecting the Future of Bioscience

    Detecting the Future of Bioscience

    Saturday, December 13, 2008
    Technical Article
    Gabriella Armin
    The potential to use antibodies as research tools has been known since the early 1890s, when Karl Landsteiner used antibodies to distinguish between the ortho and meta configurations of groups on ... read more
  • High-Throughput Cell Cycle Analysis Using a Microplate Cytometer

    High-Throughput Cell Cycle Analysis Using a Microplate Cytometer

    Friday, November 28, 2008
    Technical Article
    Paul Wylie
    The traditional method of determining the cell cycle phase of individual cells is by quantifying their total DNA content using flow cytometry. read more
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