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  • Analytical Method Development in the Quality by Design Framework

    Tuesday, December 16, 2014
    Application Note
    Torgny Fornstedt Dennis Åsberg Jörgen Samuelsson Anders Karlsson Krzysztof Kaczmarski
    The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ... read more

  • Meeting the Challenge of Biological Changes Postsampling

    Friday, May 16, 2014
    Application Note
    Marcus Söderquist
    Understanding the role of proteins, peptides, and their post-translational modifications, e.g., phosphorylations, in normal and diseased biological samples is crucial to elucidate in vivo biological ... read more

  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more

  • R&D Informatics at Molecular Med Tri-Con 2013

    Tuesday, February 26, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in... read more

  • American Society for Mass Spectrometry 2012 Product Showcase

    Tuesday, July 31, 2012
    Technical Article
    Jeanely Hunt, MS, MBA
    Mass spectrometry is a fundamental technique used by chemists and life science researchers for determining unknown samples across various research areas, such as environmental analysis, toxicology ... read more

  • Drying of Problematic Purification Samples by Lyophilization in a Centrifugal Evaporator

    Monday, June 13, 2011
    Application Note
    Induka Abeysena Rob Darrington
    Lyophilization is often the preferred method of sample drying because a high level of dryness is achieved with low residual solvent levels, and because of the light, powdery, “fluffy” finish of the ... read more

  • New Products at Pittcon® 2011

    Thursday, March 10, 2011
    Application Note
    Jeanely Hunt, MS, MBA
    The following includes some of the latest advances in laboratory instrumentation debuting at Pittcon® 2011. read more

  • Are You Attracted to Science? Attend Pittcon®—The Magnet for Scientific Innovation

    Tuesday, February 01, 2011
    Technical Article
    Penny. R Gardner
    We are very excited for Pittcon® 2011 to be back in Atlanta, GA, March 13–18, at the Georgia World Congress Center. read more

  • The Role of Analytical Instrumentation in the Life Sciences

    Saturday, November 01, 2008
    Technical Article
    Robert L. Stevenson, Ph.D. C. David Carr
    Historically, the life sciences have been qualitative in nature, seeking to identify but seldom understand quantitatively. read more

  • Fast, Practical GC and GC-MS

    Monday, January 01, 2007
    Technical Article
    Jaap de Zeeuw Martine Barnes
    Shortening run times is a welcome exercise for many laboratories, especially when sample throughput needs to be increased. read more

  • The Importance of Controlled Concentration and Drying in MALDI-TOF Applications

    Friday, July 01, 2005
    Application Note
    Steve Knight
    Matrix-assisted laser desorption/ionization-time- of-flight mass spectrometry (MALDI-TOF MS) is now an accepted and routine analysis technique for the elucidation and quantitation of biomolecules ... read more

  • A System That Helps Scientists See Drugs in Tissue Samples

    Friday, July 01, 2005
    Application Note
    Mark Springer
    For drug developers, being able to see where a drug candidate is distributed in a targeted tissue helps them better assess the potential value of that compound as a pharmaceutical product. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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