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R&D Informatics at Molecular Med Tri-Con 2013
Tuesday, February 26, 2013
Robert L. Stevenson, Ph.D.
Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in...
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Putting the “More” in Morphology: Part 2
Wednesday, April 10, 2013
Barbara Foster
Part 1 of this article discussed the impact of multiplexing morphological methods, multiparametric techniques, and supervised machine-learning to answer the question "what" is there, as well as "where...
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Challenges for Informatics in 2013: Much More Than Open-Source
Wednesday, April 17, 2013
Robert L. Stevenson, Ph.D.
As chemists and especially life scientists work with more complex systems and experiments, the huge data sets arising from high-content screening (HCS) and next-generation sequencing (NGS) challenge ...
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Choosing a Cell Isolation Kit Comes Down to Method and Marker
Monday, April 22, 2013
James Netterwald
A cell isolation kit is used to ensure that the results of cell-based downstream applications—such as cell–cell interactions, protein isolation, biochemical analysis, cell counting, host–pathogen ...
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Automated Refractive Index Calculations for Particle Size Analysis Using Laser Diffraction
Monday, June 03, 2013
Mark Bumiller
Laser diffraction has been the most common particle size analysis technique for many years. The technique is fast, flexible, and easy to use for a wide variety of sample types.
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37th International Symposium on Capillary Chromatography
Tuesday, July 02, 2013
Robert L. Stevenson, Ph.D.
Capillary chromatography is in the mainstream of the technical evolution of chromatography, driven primarily by improvements in column technology that generally precede the development of the ...
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Facilitating Scientific Information Accessibility with a Next-Generation Search Solution
Friday, July 19, 2013
Chris Stumpf
Information access is central to the success of a science-driven organization. Implementing laboratory informatics solutions that provide timely, regular, and accurate search results can have ...
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Microplate Readers Buying Tips: The Core Lab Perspective
Friday, August 16, 2013
Josh P. Roberts
Directors of core labs give their perspectives on key issues that should be considered before one purchases a microplate reader. For example, it is important for the user to determine the kinds of ...
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Bioassays and Bioanalytical Method Development 2013
Tuesday, November 12, 2013
Robert L. Stevenson, Ph.D.
Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ...
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Crossing the Chasm of Death for Biomarkers
Tuesday, August 06, 2013
Robert L. Stevenson, Ph.D.
Biomarkers, or biological markers, have intuitive appeal, since chemists and biochemists are trained to relate activity to molecular structure and metabolism. I attend over 20 scientific meetings per ...
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Integrating Microscopy Into the Analytical Scheme: A Pittcon® 2014 Microscopy Review
Monday, February 24, 2014
Barbara Foster
Microscopy is often overlooked at Pittcon®, yet of the 12,000+ scientists who attend, approximately 30% use microscopy in some form (according to ongoing research from The Microscopy & Imaging Place, ...
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Methane—A Simple Gas with Complex Problems
Tuesday, April 29, 2014
Robert L. Stevenson, Ph.D.
Natural gas (NG), which is 90+% methane, heats half of America’s households and fuels many important industrial processes including production of electricity, fertilizer, and polymers. NG is collected...
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Semantic Web Technologies as a Key to Successful Federation of Data in Life Science Organizations
Monday, September 22, 2014
Marc Lieber
The RDF Semantic Web has become an important player over the years in regard to federating different data sources using a common query federation tool, SPARQL. W3C SPARQL is now established as a ...
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GC Columns Travel to Space for Comet Rendezvous
Wednesday, November 12, 2014
Norbert Reuter
Gary Lee
Gas chromatography (GC) is a powerful analytical tool, and it’s getting out of the lab and traveling millions of miles into space as part of the Rosetta mission, a project initiated by the European ...
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LIMS and the New Monitoring Paradigm for Pharmaceuticals and Personal-Care Products
Tuesday, December 16, 2014
Colin Thurston
Jeanne Mensingh
A recent study published in the journal Environmental Pollution identified 56 active pharmaceutical ingredients (APIs) in effluent samples from 50 large wastewater treatment plants across the U.S. ...
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High-Capacity 1-mm-i.d. Polymer Monoliths for Fast Protein Separations
Friday, January 28, 2011
Christopher Pohl
Srinivasa Rao
Kelly J. Flook
Charanjit Saini
Maria Rey
Andy Woodruff
Jim Thayer
Yury Agroskin
Over the last decade, monolith technology has progressed from a promising approach conceived by Fréchet, Švec, Huber, and others to a well-developed separation tool.
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Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells
Friday, January 28, 2011
Michael Lichtenauer
Stefanie Nickl
Konrad Hoetzenecker
Andreas Mangold
Andreas Mitterbauer
Stefan Hacker
Matthias Zimmermann
Hendrik Jan Ankersmit
Phosphate-buffered saline (PBS), a buffer solution commonly used in many biological research fields, contains monobasic potassium phosphate, sodium chloride, and dibasic sodium phosphate.
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Statistics in Analytical Chemistry: Part 41—Blanks (Concluded)
Friday, January 28, 2011
David Coleman
Lynn Vanatta
The previous article (American Laboratory, Oct 2010) left off with two interesting questions: 1) How does an analyst decide whether a positive response for a blank is low enough to be ignored? and 2) ...
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Statistics in Analytical Chemistry: Part 39—Inexact Replicates: Example
Thursday, August 12, 2010
David Coleman
Lynn Vanatta
The previous installment (Part 38, American Laboratory, May 2010) outlined the regression-diagnostic steps needed when replicates are not exact.
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Use of a Virtual Instrument to Measure the Mass Concentration of Nitrogen Dioxide
Sunday, August 01, 2010
Olga Kyselova
Grazina Smolianskiene
Danute Adamoniene
Danguole Kaziukoniene
Aleksej Romanov
Scientists and engineers around the world use computer software for research, design, and production. Analytical equipment manufacturers are developing the latest tools that make possible proper use ...
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