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  • High-Throughput Drug Screening of Multicellular Tumor Spheroids

    Tuesday, September 27, 2016
    Application Note
    Ana Maria P. Pardo Hannah J. Gitschier David H. Randle Terry Riss
    Three-dimensional (3-D) culture models are increasingly being used for drug discovery in oncology, as they better represent the complexity of the in vivo microenvironment of solid tumors. read more
  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more
  • How Solid-Phase Extraction Affects Challenges in Bioanalysis

    Wednesday, February 05, 2014
    Application Note
    Mike Oliver Tim Liddicoat Ken Meadows
    Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more
  • Product Intelligence: Solid Phase Extraction Systems

    Monday, February 25, 2013
    Technical Article
    Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more
  • Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more
  • High-Precision, High-Sensitivity Measurements of Lead and Cadmium in Honey by GFAAS

    Monday, March 01, 2010
    Application Note
    Zhi-Gang Ouyang Zhong-Lan Chen Ying Wu
    Honey is a natural substance produced in honeycombs by honeybees under special conditions. For centuries, honey has often been referred to as nature’s medicine. It is known to help heal bronchial ... read more
  • Statistics in Analytical Chemistry: Part 25—Calibration Summary

    Thursday, February 01, 2007
    Technical Article
    David Coleman Lynn Vanatta
    In a modern chemical-analysis laboratory, virtually all of the testing equipment must be calibrated periodically. read more
  • Centrifuge Safety and Security

    Thursday, February 01, 2007
    Application Note
    Tammy Goodman
    For laboratories around the world, increasing health and safety legislation requires that equipment be operated and maintained so that every step is taken to maximize safety and security. read more
  • Reagent-Free Ion Chromatography Systems With Eluent Regeneration: RFIC-ER Systems

    Thursday, February 01, 2007
    Application Note
    Yan Liu Zhongqing Lu Chris Pohl John Madden Navette Shirakawa
    Since the introduction of ion chromatography (IC) in 1975, Dionex Corp. (Sunnyvale, CA) has continued to improve the performance of IC systems while developing new capabilities for the determination ... read more
  • The Nanoliter Syringes

    Thursday, February 01, 2007
    Technical Article
    Andrew D. Sauter
    Following an informal collaboration with Affymax (Palo Alto, CA), Agilent Technologies (Palo Alto, CA), and Chem-Space Associates (Pittsburgh, PA), studying electrospray ionization 1 (ESI), the ... read more
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