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  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more

  • Protein Aggregation at PepTalk 2014

    Monday, March 31, 2014
    Technical Article
    Robert L. Stevenson, Ph.D.
    Quantitative analysis of subvisible particles is an important unsolved problem, as discussed in the Particle Analysis track of PepTalk 2014, held January 12–17 at the Renaissance Hotel and Palm ... read more

  • How Solid-Phase Extraction Affects Challenges in Bioanalysis

    Wednesday, February 05, 2014
    Application Note
    Mike Oliver Tim Liddicoat Ken Meadows
    Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more

  • Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more

  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more

  • Product Intelligence: Solid Phase Extraction Systems

    Monday, February 25, 2013
    Technical Article
    Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more

  • High-Content Analysis (HCA 2013): 3-D Reduces the Gap Between In Vitro and In Vivo

    Tuesday, February 05, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The 10th High-Content Analysis meeting attracted about 300 scientists to San Francisco’s Fairmont Hotel (January 8–11, 2013). A Venn diagram of attendees would certainly include overlapping circles ... read more

  • Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more

  • Diagnostic, Prognostic, and Predictive: The Dynamic Role of Molecular Technology in Personalized ...

    Tuesday, January 10, 2012
    Technical Article
    T. Keith Brock
    The expected growth of molecular techniques over the next 10 years will have a profound impact on clinical decision-making. read more

  • Enterprise Thinking: Driving Open Standards Adoption in the Laboratory

    Wednesday, September 01, 2010
    Application Note
    Trish Meek Séamus Mac Conaonaigh
    With the continued rise in the cost of drug research and development, pharmaceutical, biotechnology, and research companies are rethinking the way they do business. read more

  • Improving FTIR Operation With a Contaminant Analysis Program

    Wednesday, September 01, 2010
    Application Note
    John Monti
    Spectrum search (library search) is a procedure often used in contaminant analysis. It consists of using the search function included in Fourier transform infrared (FTIR) software or specialized ... read more

  • Effective Forensic Sample Tracking and Handling

    Wednesday, September 01, 2010
    Application Note
    Tal Murthy Brian Hewson
    With implications for the success of a legal case, forensic samples must be stored under optimal conditions to avoid DNA deterioration. Failure to maintain proper storage conditions can result in ... read more

  • Benefits of an Integrated Laboratory (iLAB)

    Wednesday, September 01, 2010
    Application Note
    Robert Pavlis
    An iLAB, or integrated laboratory, is a new type of laboratory informatics system—a total laboratory automation system. The value of an iLAB can best be appreciated by exploring four key problems with... read more

  • Challenging Chromatographic Peak Integration

    Wednesday, September 01, 2010
    Application Note
    Shaun Quinn
    Integration is a fundamental task that all chromatographers perform on a daily basis. Due to faster chromatography, which is creating more data every day, the amount of time spent on integration is ... read more

  • Identifying Trace Compounds in Complex Mixtures With MS Data-Processing Software

    Wednesday, September 01, 2010
    Application Note
    Gareth M. Roberts
    With the ultimate aim of protecting workers, consumers, and the environment, industry regulations are continually expanding with respect to monitoring the volatile organic compounds (VOCs) emitted by ... read more
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