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Thin-Layer Chromatography/Mass Spectrometry Analysis of Sample Mixtures Using a Compact Mass ...
Tuesday, May 12, 2015
Application Note
Changtong Hao Nigel Sousou Daniel Eikel Jack Henion
Thin-layer chromatography (TLC) is a planar chromatographic technique used to separate the components of a mixture by employing a thin stationary phase supported by an inert backing. It can be ... read more
High-Throughput Tools for Optimizing Drug Nanosuspensions
Thursday, February 19, 2015
Application Note
Dennis H. Leung Timothy Rhodes Annette Bak
Inadequate absorption and bioavailability often make it difficult to deliver the drug to the target in vivo and pose significant challenges to the discovery and development of new drugs. A number of ... read more
Sample Processing at Pittcon® 2014
Tuesday, May 06, 2014
Application Note
Robert L. Stevenson, Ph.D.
The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more
How Solid-Phase Extraction Affects Challenges in Bioanalysis
Wednesday, February 05, 2014
Application Note
Mike Oliver Tim Liddicoat Ken Meadows
Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more
Determination of Total Mercury Content and Trace Metal Analysis in Wood Materials—Part 1: ICP-OES ...
Tuesday, August 06, 2013
Application Note
Heidi Fleischer Kerstin Thurow
The transition metal mercury has many exciting properties; for example, it is the only known metal that is liquid at room temperature, hence its use in thermometers. Other common applications are in ... read more
R&D Informatics at Molecular Med Tri-Con 2013
Tuesday, February 26, 2013
Technical Article
Robert L. Stevenson, Ph.D.
Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in... read more
Product Intelligence: Solid Phase Extraction Systems
Monday, February 25, 2013
Technical Article

Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more
Optimizing HPLC Sample Preparation
Monday, February 06, 2012
Technical Article
Caitlin Smith
Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more
Connecting the Dots With a Foundation for Biological Registration
Tuesday, August 02, 2011
Technical Article
Frank Brown John Conway
The last decade has seen huge advances in biological research. The advent of genomics and proteomics,as well as experimental approaches such as next-generation sequencing and high-throughput screening... read more
A UV Shadowing Technique Using a CCD Imaging System
Monday, April 04, 2011
Application Note
Lindsey Bunn Afaf El-Sagheer
To visualize DNA and RNA on a gel requires the use of a dye or a radiolabel. read more
Increased Throughput in Method 8270 Analysis
Monday, January 01, 2007
Application Note
William D. Goodman Frank DeLorenzo
Method 8270 is a GC-MS method created by the U.S. EPA Office of Solid Waste for the analysis of semivolatile organics by gas chromatography-mass spectrometry. read more
Automated Chemical Ionization in GC-MS
Monday, January 01, 2007
Application Note
Chris Sandy Jean-Francois Garnier Bernhard Rothweiler Fred Feyerherm Sihem Ben Mahmoud Harry F. Prest
Gas chromatography with mass spectrometric detection using chemical ionization (CI) has demonstrated great utility in a wide variety of application areas ranging from forensics to environmental to ... read more