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  • High-Throughput Tools for Optimizing Drug Nanosuspensions

    Thursday, February 19, 2015
    Application Note
    Dennis H. Leung Timothy Rhodes Annette Bak
    Inadequate absorption and bioavailability often make it difficult to deliver the drug to the target in vivo and pose significant challenges to the discovery and development of new drugs. A number of ... read more

  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more

  • How Solid-Phase Extraction Affects Challenges in Bioanalysis

    Wednesday, February 05, 2014
    Application Note
    Mike Oliver Tim Liddicoat Ken Meadows
    Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more

  • Evaluation of Antibiotic-Free Cell Cultures in Manual and Automated Cell Handling

    Monday, October 28, 2013
    Application Note
    Kerstin Thurow Ricarda Lehmann Leonie Vetter Luisa Person
    Antibiotics are frequently added to cell culture media; the greatest benefit to this is that it suppresses contamination. However, routine use of antibiotics is associated with the development of ... read more

  • Pittcon 2013®: Developments in Liquid Chromatography

    Monday, May 13, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The first commercial liquid chromatograph was probably an amino acid analyzer. These ion exchange chromatographs were so specialized that they had almost no impact on chemical analysis outside of ... read more

  • Advances in Gas Chromatography Instrumentation at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The buzzwords for Pittcon® 2013 in gas chromatography instrumentation were “smaller,” “portable,” and “helium.” Despite the fact that some of the major vendors did not exhibit, others were on hand ... read more

  • What’s New in Optical Spectroscopy at Pittcon® 2013?

    Friday, May 10, 2013
    Technical Article
    Mark Fisher
    Soon after the first spectrophotometer was built, the challenge of improving it began. How could we make spectrophotometers better? Could we make them smaller, faster, or perhaps improve the ... read more

  • Advances in Mass Spectrometry at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Brian Musselman
    This has been a busy year for mass spectrometry companies and with the Triennial International Conference on Mass Spectrometry occurring last fall. This year at Pittcon®, several new high-end mass ... read more

  • Exhibition of Chromatography Columns at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The technology and market for liquid chromatography columns continue to mature, with applications-specific columns on the rise. The chromatography columns target specific assays in the clinical ... read more

  • Awarding Innovation: The Pittcon® 2013 Editors’ Awards

    Friday, May 10, 2013
    Technical Article
    Marian Nardozzi
    Pittcon® offers many different award ceremonies for outstanding scientific achievement to members of the scientific community; however, there is only one award for innovations in instrumentation. The... read more

  • Sample Prep for LC, GC, and SFC at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more

  • Product Intelligence: Solid Phase Extraction Systems

    Monday, February 25, 2013
    Technical Article
    Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more

  • Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more

  • Rapid Enantiomeric Excess Determination of D- and L-Proline Using Electrospray Ionization–Mass ...

    Thursday, September 01, 2011
    Technical Article
    Heidi Fleischer Kerstin Thurow
    The enantiomeric composition of proline is commonly determined using conventional analytical methods such as HPLC, GC, and CE. read more
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