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  • Electronic Pipetting: The Call for Innovation

    Electronic Pipetting: The Call for Innovation

    Thursday, February 27, 2014
    Application Note
    Paula Heimler
    Take a close look around most laboratories and you will find an old, barely used fixture. No one knows who ordered it or who it belongs to. It is yellowed, dusty, and top heavy, with a small keyboard ... read more
  • Bioassays and Bioanalytical Method Development 2013

    Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more
  • Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays

    Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays

    Friday, June 07, 2013
    Application Note
    Amedeo Cappione, Masaharu Mabuchi, David Briggs, Timothy Nadler
    Many protein detection methods, including Western blotting, flow cytometry, ELISA, and immunohistochemistry, require the use of target-specific probes, such as antibodies, that are detected via two-... read more
  • Putting the “More” in Morphology: Part 1

    Putting the “More” in Morphology: Part 1

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Segmentation, the ability to define the unique features in a region of interest, has always been the greatest challenge in image analysis and quantitation. A new suite of tools, available from ... read more
  • Automated Botulinum Neurotoxin Detection

    Automated Botulinum Neurotoxin Detection

    Monday, February 25, 2013
    Technical Article
    Karine Bagramyan, Aneela Reddy, Dobrin Nedelkov, Markus Kalkum
    Botulinum neurotoxin (BoNT) is undoubtedly the most potent biological toxin known. Intravenously injected it could paralyze and kill a human being at a dose of just 1.2 ng BoNT per kg body weight. read more
  • Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Friday, February 08, 2013
    Technical Article
    Robert L. Stevenson
    Most commonly, laboratory automation involves a few hundred wells run for a specific purpose. SLAS 2013, the meeting of the Society for Laboratory Automation and Screening, was held at the Gaylord ... read more
  • Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Second-Generation Expanded Bed Adsorption Scales from Lab to Plant

    Thursday, January 17, 2013
    Application Note
    Robert L. Stevenson
    Expanded bed adsorption (EBA) was introduced in 1999 with adsorbents that were used for pressure-driven packed beds. These had densities in the range of 1.1–1.5 g/mL, which was not much higher than ... read more
  • Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory

    Monday, December 24, 2012
    Technical Article
    Laurent Baron, Bobby Chavli, Lois Tack, Annette Summers
    For years, forensic laboratories in the U.S. have struggled to reduce DNA sample processing backlogs and human errors, both of which hinder timely and reliable criminal convictions. read more
  • An Ultrasensitive Immunoassay Detection System for Biomarkers Utilizing Raman Scattering Methods

    An Ultrasensitive Immunoassay Detection System for Biomarkers Utilizing Raman Scattering Methods

    Wednesday, October 31, 2012
    Technical Article
    Samar Kundu, Charles Ginsburgh, Sandra Lynch, Neal Siegel
    Detection of low levels of biomarkers utilizing enzyme linked immunosorbent assay (ELISA) technology is demonstrated through the use of Raman scattering techniques and a convertible substrate for ... read more
  • Optimizing HPLC Sample Preparation

    Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more
  • Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Effect of PBS Solutions on Chemokine Secretion of Human Peripheral Blood Mononuclear Cells

    Friday, January 28, 2011
    Technical Article
    Michael Lichtenauer, Stefanie Nickl, Konrad Hoetzenecker, Andreas Mangold, Andreas Mitterbauer, Stefan Hacker, Matthias Zimmermann, Hendrik Jan Ankersmit
    Phosphate-buffered saline (PBS), a buffer solution commonly used in many biological research fields, contains monobasic potassium phosphate, sodium chloride, and dibasic sodium phosphate. read more
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