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  • Analytical Method Development in the Quality by Design Framework

    Tuesday, December 16, 2014
    Application Note
    Torgny Fornstedt Dennis Åsberg Jörgen Samuelsson Anders Karlsson Krzysztof Kaczmarski
    The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ... read more

  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more

  • R&D Informatics at Molecular Med Tri-Con 2013

    Tuesday, February 26, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in... read more

  • Drying of Problematic Purification Samples by Lyophilization in a Centrifugal Evaporator

    Monday, June 13, 2011
    Application Note
    Induka Abeysena Rob Darrington
    Lyophilization is often the preferred method of sample drying because a high level of dryness is achieved with low residual solvent levels, and because of the light, powdery, “fluffy” finish of the ... read more

  • High-Content Analysis Comes Full Circle in Only Eight Years

    Monday, April 18, 2011
    Technical Article
    Robert L. Stevenson, Ph.D.
    In eight short years, high-content analysis (HCA) has circled back to its roots, where many practitioners are again using personal instruments. read more

  • Providing Purge Gas for FTIR Systems

    Monday, April 18, 2011
    Technical Article
    Peter Froehlich Kim Myers
    While a Fourier transform infrared (FTIR) spectrophotometer provides a number of benefits relative to a scanning IR spectrophotometer,a significant disadvantage of an FTIR system is that the presence ... read more

  • Are You Attracted to Science? Attend Pittcon®—The Magnet for Scientific Innovation

    Tuesday, February 01, 2011
    Technical Article
    Penny. R Gardner
    We are very excited for Pittcon® 2011 to be back in Atlanta, GA, March 13–18, at the Georgia World Congress Center. read more

  • Tips to Prevent Streaking on 2-D Gels

    Tuesday, November 01, 2005
    Application Note
    Tom Berkelman Mary Grace Brubacher Haiyin Chang Tim Cross William Strong
    The most common problem encountered with 2-D gels is protein streaking, whether in the horizontal or vertical direction. read more

  • An Automated Alternative to SDS-PAGE for Protein Analysis

    Tuesday, March 01, 2005
    Technical Article
    Sang Jeong Sherri Biondi Jim Mikkelsen Bahram Fathollahi Adrian Winoto Michael Spaid Andrea Chow
    Now that the Human Genome Project is finished, the next important phase is understanding the expression and function of proteins. read more
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