Article Archives

Filter

Hide Filter

  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more

  • Sample Prep for LC, GC, and SFC at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more

  • Focus on Liquid Handling and 3-D Imaging at SLAS 2013

    Friday, February 08, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Most commonly, laboratory automation involves a few hundred wells run for a specific purpose. SLAS 2013, the meeting of the Society for Laboratory Automation and Screening, was held at the Gaylord ... read more

  • New Instrumentation and Applications at HPLC 2012

    Friday, August 10, 2012
    Technical Article
    Robert L. Stevenson, Ph.D.
    A marketplace is usually dynamic, with a cross-current of disparate interests meeting to find mutual satisfaction. read more

  • Characterizing Protein–Protein Interactions Via Static Light Scattering: Inhibition Kinetics and ...

    Tuesday, February 02, 2010
    Technical Article
    Dan Some Amy Hanlon
    Quantification of the kinetic rates of protein association, dissociation, and aggregation is an essential factor in understanding and ultimately manipulating these phenomena. A variety of measurement ... read more

  • An Automated Surface Plasmon Resonance-Based System

    Tuesday, December 01, 2009
    Application Note
    John Quinn Aaron Martin Nathan Gillock Jeffery Havard
    Over the past 15 years, label-free, real-time biomolecular interaction analysis has established itself across a broad spectrum of disciplines from drug discovery to basic life science R&D. read more

  • Evaluating Candidate Lead Compounds by Rapid Analysis of Drug Interactions with Human Serum Albumin

    Tuesday, April 22, 2008
    Technical Article
    Vered Bronner Oded Nahshol Tsafrir Bravman
    Human serum albumin (HSA) plays a fundamental role in the transport of drugs, metabolites, and endogenous ligands. Binding to HSA controls the free, active concentration of a drug; provides a ... read more

  • Image Analysis of Neurite Branching: High-Content Screening at High Speed

    Thursday, September 01, 2005
    Application Note
    Pascal Vallotton Leanne Bischof Michael Buckley Ryan Lagerstrom Changming Sun Hugues Talbot Dadong Wang
    Automated image analysis is becoming a central tool for quantifying the effect of candidate drugs on cells. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
  • <<
  • >>