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Title
A Thermal Analysis Technique That Combines Differential Scanning Calorimetry and Light Microscopy
Wednesday, June 24, 2015
Mike Reading
Duncan Stacey
Thermal analysis by structural characterization (TASC) combines with differential scanning calorimetry (DSC) and light microscopy to provide a powerful technique for characterizing polymers, ...
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Preview of the 24th International Light Scattering Colloquium: An Interview With Philip Wyatt of Wyatt Technology Corp.
Wednesday, September 30, 2015
Robert L. Stevenson, Ph.D.
Light scattering is the most powerful tool for characterizing the size, shape, interactions and function of nanoparticles.
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Diagnostics From the Chemistry Laboratory to the Point of Care: An Interview With Shane Needham of Alturas Analytics, Inc.
Friday, September 25, 2015
Robert L. Stevenson, Ph.D.
The disease discovery and therapy workflow is lengthy and convoluted, with the potential for technical, regulatory and turf issues.
read more
Fighting Resistance With Calorimetry: New Tools for Antimicrobial Drug Development
Thursday, November 19, 2015
Magnus Jansson
Antibiotic-resistant bacteria are a growing concern, and with good reason—an estimated 23,000 deaths and two million illnesses occur annually in the U.S.
read more
Statistics in the Laboratory: Control Charts, Part 2
Wednesday, April 06, 2016
Stanley N. Deming
In the previous column (January/February 2016), we looked at the basic ideas behind control charts and saw how to construct a common X-bar and R chart.
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Measuring Organic Carbon: A Brief History and Discussion of Methodologies
Monday, May 02, 2016
William Lipps
Total organic carbon (TOC) is a rapid method that analyzes for organic carbon and expresses the result as the amount of carbon found.
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Statistics in the Laboratory: Control Charts, Part 3
Thursday, May 26, 2016
Stanley N. Deming
In the previous two columns (January/February and April 2016), we looked at the basic ideas behind control charts, saw how to construct the common X-bar and R charts and discovered that only two ...
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Trends in Biobanking
Tuesday, July 26, 2016
Martin Frey
In the early days of biobanking, biological sample collections were usually associated with a specific research area and stored near the collection point.
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Detection of Malathion Using Acetylcholinesterase-Immobilized Sol-Gel Film
Monday, January 05, 2015
Dan Xiao
Martin M.F. Choi
Jie He
Hongyan Yuan
Runguo Lin
For the past two decades, enzyme electrode development and applications have received a great deal of attention. The conventional enzyme immobilization method depends on the preparation of an enzyme...
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Statistics in the Laboratory: Scedasticity
Friday, August 24, 2018
Stanley N. Deming
Homoscedastic and heteroscedastic—if nothing else, these are two good adjectives for word games.
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Statistics in the Laboratory: The Apparent Capability of an Industrial Process
Monday, January 16, 2017
Stanley N. Deming
It’s important to realize that information gets filtered and distorted by the inherent behavior of a measurement process.
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Timeline for Building the Francis Crick Institute
Tuesday, January 17, 2017
Robert L. Stevenson, Ph.D.
The UK Centre for Medical Research and Innovation (UKCMRI) (now known as the Francis Crick Institute) was established in response to the need for an organization dedicated to improving healthcare in ...
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Analytical Method Transfer: Bioprocessing’s Key Enabling Technology
Wednesday, February 15, 2017
Robert L. Stevenson, Ph.D.
Analytical biochemistry is the key enabling technology supporting the biotech revolution.
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Fast GC Adopted for Wine Cork Analysis
Thursday, June 01, 2017
A fast chromatography system can analyze each cork on a customer production line in seconds—a dramatic improvement over previous testing that typically required up to 14 minutes per batch.
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Potential of 3-D Cell Culture in Research and Therapy
Tuesday, September 05, 2017
Richard M. Eglen
Tools and technologies for 3-D cell culture have rapidly evolved in the past three years or so, elevating its value in drug and toxicity screening as well as stem cell culture and differentiation, ...
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Hydrogen/Deuterium Exchange-MS for Biologics: Higher-Order Structure Analysis and Epitope Mapping
Monday, January 01, 2018
Yoshitomo Hamuro
Biologics are the fastest-growing sector in the pharmaceutical industry, with global sales approaching $200 billion and making up about 20% of all pharmaceuticals.
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Introduction of NIST 17—A Major Update of Mass Spectral Libraries and Software—at the 65th ASMS Conference on Mass Spectrometry and Allied Topics
Friday, August 04, 2017
O. David Sparkman
At the 65th American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics, held June 4–8, 2017, in Indianapolis, IN, the National Institute of Standards and Technology’s (...
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What Lab Managers Should Know About Managing and Reviewing Orphan Chromatographic Data in Light of the FDA’s Quality Metrics Initiative
Monday, July 09, 2018
Heather Longden
Pharmaceutical industry laboratory managers have likely been following the FDA’s Quality Metrics Initiative, which aims to prevent and mitigate drug shortages and encourage manufacturers to adopt ...
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USP <232> and <233> are Issued: Quo Vadis?
Thursday, May 31, 2018
Robert L. Stevenson, Ph.D.
This article explores whether to develop and support assays in-house or outsource them.
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Statistics in the Laboratory: Confidence Interval of the Mean
Wednesday, June 19, 2019
Stanley N. Deming
Estimated means are often used for making quantitative decisions (e.g., to decide if something meets specifications).
read more
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