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  • Electronic Pipetting: The Call for Innovation

    Thursday, February 27, 2014
    Application Note
    Paula Heimler
    Take a close look around most laboratories and you will find an old, barely used fixture. No one knows who ordered it or who it belongs to. It is yellowed, dusty, and top heavy, with a small keyboard ... read more

  • Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more

  • Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays

    Friday, June 07, 2013
    Application Note
    Amedeo Cappione Masaharu Mabuchi David Briggs Timothy Nadler
    Many protein detection methods, including Western blotting, flow cytometry, ELISA, and immunohistochemistry, require the use of target-specific probes, such as antibodies, that are detected via two-... read more

  • Putting the “More” in Morphology: Part 2

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Part 1 of this article discussed the impact of multiplexing morphological methods, multiparametric techniques, and supervised machine-learning to answer the question "what" is there, as well as "where... read more

  • Putting the “More” in Morphology: Part 1

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Segmentation, the ability to define the unique features in a region of interest, has always been the greatest challenge in image analysis and quantitation. A new suite of tools, available from ... read more

  • An Ultrasensitive Immunoassay Detection System for Biomarkers Utilizing Raman Scattering Methods

    Wednesday, October 31, 2012
    Technical Article
    Samar Kundu Charles Ginsburgh Sandra Lynch Neal Siegel
    Detection of low levels of biomarkers utilizing enzyme linked immunosorbent assay (ELISA) technology is demonstrated through the use of Raman scattering techniques and a convertible substrate for ... read more

  • Light-Emitting Diodes: A New Solution for Fluorescence

    Saturday, October 01, 2011
    Technical Article
    Barbara Foster
    From the dramatic increase in new fluorophores to the proliferation of techniques like total internal reflection fluorescence (TIRF), photoactivated localization microscopy (PALM), and stochastic... read more

  • Fluorescence Microscopy: Solving Common Documentation Challenges

    Sunday, November 01, 2009
    Application Note
    Mark Clymer
    Fluorescence has proven to be a useful technique for identifying, tracking, and studying molecules of interest in biological specimens. In fact, fluorescence is among the fastest growing microscopy ... read more

  • Advances in Cryo-SEM: From Micrometers to Nanometers

    Sunday, November 01, 2009
    Application Note
    Jens Greiser
    Science is driving the demand for nanoscale resolution. Cryo-scanning electron microscopy (cryo-SEM), which combines the high-performance imaging of scanning electron microscopy (SEM) with cryogenic ... read more

  • Addressing New Challenges in the Field of Growth Promoters in Biological Samples

    Sunday, November 01, 2009
    Technical Article
    Fabrice Monteau Jean-Philippe Antignac Gaud Pinel Paul Silcock Peter Hancock Bruno Le Bizec
    The safety of our food supply can no longer be taken for granted. As the world changes and populations continue to grow, so will the responsibility of organizations to meet the demand for safe ... read more
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