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  • Improving the Crystallization Process for Optimal Drug Development

    Friday, March 28, 2014
    Application Note
    Michael Collazo Soheila Vaezeslami Sarah Burl
    Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ... read more

  • Neutron Crystallography Contributes to Drug Design

    Monday, January 07, 2013
    Technical Article
    Zoe Fisher
    Carbonic anhydrases are a large group of enzymes that are expressed in humans. Carbonic anhydrase (CA) catalyzes the reversible hydration of CO2 to make bicarbonate and a proton. As such, this enzyme ... read more

  • Pittcon® 2011 Exposition: New Product Introductions in Optical Spectroscopy and Mass Spectrometry

    Monday, May 09, 2011
    Technical Article
    George M. Frame II Eileen M. Skelly Frame
    Of the 979 exhibitors at Pittcon® 2011, held March 13–18 in Atlanta, GA, 115 were first-time exhibitors, and more than 200 identified themselves as having something to do with spectroscopy, from ... read more

  • A New-Generation Microwave Digestion System

    Friday, January 28, 2011
    Application Note
    Carl Chan
    Since the laboratory microwave digestion system first became commercially available in the 1980s, sample preparation has become mainstream, and the preparation of samples for atomic spectroscopy has ... read more

  • Increasing Application of X-Ray Powder Diffraction in the Pharmaceutical Industry

    Wednesday, June 01, 2005
    Application Note
    Brian Litteer Detlef Beckers
    X-ray powder diffraction has recently been propelled to the forefront as an analytical tool in the pharmaceutical industry for a wide range of applications. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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