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  • Smart Sample Prep in Chromatography: An Automated Liquid–Liquid Extraction Technique for ...

    Friday, February 19, 2016
    Application Note
    Emmanuel Varesio Sandra Jahn Sandrine Cudré Gérard Hopfgartner Renzo Picenoni Guenter Boehm
    As laboratories continue to be asked to increase productivity and the analysis power that is available with advanced chromatography systems continues to grow, the focus for many scientists is firmly ... read more

  • Computer-Assisted Structure Elucidation in Routine Analysis

    Tuesday, January 26, 2016
    Application Note
    Patrick Wheeler Steve Hayward Mikhail Elyashberg
    The elucidation of unknown structures, especially those with novel moieties found in natural products, often results in initially incorrect published structures, which then require either exhaustive ... read more

  • Raman and Infrared Spectra: Capturing the Artistry of Spectral Interpretation

    Tuesday, October 02, 2012
    Application Note
    Michael Boruta
    This article focuses on a means of capturing spectrum-to-structure correlations for Raman and infrared spectra. It discusses methods that can be used to obtain, archive, and retrieve this knowledge so... read more

  • Automated Structure Verification by NMR, Part 1: Lead Optimization Support in Drug Discovery

    Tuesday, January 10, 2012
    Technical Article
    Philip Keyes Michael Messinger Gonzalo Hernandez
    The pharmaceutical industry has always relied on testing and evaluating novel compounds in a wide range of chemical space to feed its pipelines. read more

  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more

  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more

  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more

  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more

  • Dielectrophoretic Force Microscopy

    Wednesday, January 19, 2005
    Application Note
    Al M. Hilton Brian P. Lynch Garth J. Simpson
    Dielectrophoresis (DEP), the force exerted on a polarizable particle in a nonuniform electric field, has been used with great success in recent years to manipulate and separate cells and biomolecules. read more
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