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Heidi Fleischer
Heidi Fleischer
Articles by Heidi Fleischer
Theory and Practical Applications of Automation Solutions in Analytical Measurements
Wednesday, July 24, 2019
Automated systems for sample preparation and analytical measurements must follow special protocols due to their complex process structure with multiple subprocesses.
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Sample Preparation and Measurement of Cholesterol in Pig Bile Using SPE and GC/MS
Thursday, February 21, 2019
A sample cleanup method by solid-phase extraction and a GC/MS measurement method for cholesterol determination were developed and validated.
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A Flexible Measurement System for Online Reaction Monitoring Using ESI-MS and ICP-MS
Tuesday, August 07, 2018
An online reaction monitoring system can be coupled to several measurement instruments using an electrospray ionization mass spectrometer (ESI-MS) to receive structural information and an inductively ...
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Determination of Calcium and Trace Metals in Clogged Biliary Endoprostheses Using ICP/MS
Wednesday, July 26, 2017
This article describes a method used to determine calcium and trace metals using inductively coupled plasma/mass spectrometry (ICP/MS) to investigate the elementary composition of encrustations in ...
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Integration of a Dilution Module in a Mass Spectrometry-Based Online Reaction Monitoring System
Friday, January 20, 2017
A dilution module based primarily on a mass rate attenuator solves the problem of high concentration solution to the mass spectrometer. The low-flow compensation approach was used to circumvent the ...
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Automated Sample Preparation Using a Dual-Arm Robotic Platform
Monday, May 02, 2016
As described in this article, the CSDA10F dual-arm robot can utilize pipets, syringes, vials, microplates and thermal shakers (including pipets and a thermal shaker designed for manual use) to prepare...
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Evaluation of an Automated Solid-Phase Extraction Method Using Positive Pressure
Wednesday, April 08, 2015
Investigations for the determination of drugs in real samples, while gaining in importance, are limited by time and sample throughput. In response to this, the authors developed an automated solid-...
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Determination of Total Mercury Content in Wood Materials—Part 3: Miniaturization Using ICP-MS
Monday, August 04, 2014
High-throughput screening processes have become an essential tool in the pharmaceutical industry and clinical laboratory. High-throughput screening, or HTS, is used in drug discovery as well as in ...
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Qualitative and Quantitative Determination of Methacrylates in Dental Filling Materials
Monday, March 03, 2014
Various species of methacrylates are widely used in dentistry as filling materials. These consist mainly of an organic matrix, based on a monomer system of methacrylates and inorganic additives.
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Determination of Total Mercury Content in Wood Materials, Part 2: ICP-MS—A Multielement Method
Thursday, August 29, 2013
Even in minor concentrations, elemental mercury and inorganic and organic bound mercury can have harmful biological effects on organisms. Mercury and other toxic elements can enter the environment ...
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Determination of Total Mercury Content and Trace Metal Analysis in Wood Materials—Part 1: ICP-OES Using Mercury Cold Vapor
Tuesday, August 06, 2013
The transition metal mercury has many exciting properties; for example, it is the only known metal that is liquid at room temperature, hence its use in thermometers. Other common applications are in ...
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Rapid Enantiomeric Excess Determination of D- and L-Proline Using Electrospray Ionization–Mass Spectrometry
Thursday, September 01, 2011
The enantiomeric composition of proline is commonly determined using conventional analytical methods such as HPLC, GC, and CE.
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High-Throughput Screening Applications for Enantiomeric Excess Determination Using ESI-MS
Thursday, June 18, 2009
In the past decades, high-throughput screening (HTS) applications have been established in many fields of drug development. Thus, suitable qualitative and quantitative analytical methods have become ...
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