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Plate Washing in 1536: Evaluation of a Double-Column Aspirator Head
Thursday, October 22, 2009
Plate assays (1536-well) that require washing (i.e., enzyme-linked immunosorbent assays [ELISAs] and cell-based), are not routinely implemented in high-throughput screening laboratories due to the ...
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Capillary Rheometry: Analysis of Low-Viscosity Fluids, and Viscous Liquids and Melts at High Shear Rates
Thursday, October 01, 2009
Rheology is defined as the study of the flow and deformation of fluids. Based on the need to quickly and accurately set and control processing conditions, optimize product performance, and/or ...
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A Fast Method for Determination of Melamine in Liquid Milk and Milk Powder by HPLC With UV Detection
Thursday, October 01, 2009
Melamine discovered in baby formula and products containing milk has led to one of the largest worldwide food recalls in history. Some manufacturers in China illegally added melamine, an ingredient ...
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Dietary Supplement Standard Reference Materials
Thursday, October 01, 2009
In 1994, the U.S. Congress enacted the Dietary Supplement Health and Education Act (DSHEA) to "protect the right of access of consumers to safe dietary supplements." One way in which this is expected ...
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Reduced Carryover Using an LC Autosampler System
Thursday, October 01, 2009
Recent high-sensitivity and high-throughput trends in liquid chromatography,influenced largely by the latest interfacing technologies of mass spectrometry, seem to demand further improvements in ...
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Impurity Evaluation of Heparin Sodium by Anion Exchange Chromatography
Thursday, October 01, 2009
As a blood-thinning drug, heparin and its derivative, low-molecular-weight heparin (LMWH), have been widely used for decades during surgery and kidney dialysis.
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Volume 41, Number 11
Thursday, October 01, 2009
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Quality Checking for High-Throughput Screening
Friday, September 25, 2009
Chemical screening requires methods for the liquid handling of chemical compounds.
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Transferability of Pipet Calibrations and Proficiency of Operators: Prerequisites for Method Validations and Method Transfers
Friday, September 25, 2009
Data quality and integrity are among the most important issues for any laboratory, and one of the most obvious ways to maintain quality in a laboratory setting is regular instrument calibration.
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Quality Checking for High-Throughput Screening
Friday, September 25, 2009
Chemical screening requires methods for the liquid handling of chemical compounds.
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1-mm-i.d. Monolithic HPLC Columns for High-Efficiency Protein Separations
Tuesday, September 01, 2009
The preparation of monolithic separation media for HPLC composed of a single, continuous polymer macroporous support has been reported since the late 1960s. Due to its unique material properties, ...
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Knowledge Management and Efficiency Gains
Tuesday, September 01, 2009
In the face of escalating R&D costs, currently estimated at $800 million U.S. to produce a new drug, the life science discovery industry is constantly searching for ways to control expenditure, ...
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Design and Application of a Virtual Ion Meter Based on Graphical Programming Software
Tuesday, September 01, 2009
The ion meter is one of the most widely used analytical instruments in scientific research and routine laboratory practice in the biomedical, chemical, and environmental fields. In general, the data ...
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Extracting Greater Value From Scientific Data: An Optimized Approach
Tuesday, September 01, 2009
Today’s pharmaceutical, chemicals, materials, and consumer packaged goods (CPG) organizations must deal with a number of competing challenges: From a business perspective, they face growing pressures ...
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A Nondestructive Technique for the Detection of Metallic Impurities in Alloys
Tuesday, September 01, 2009
Examples of welds contaminated with small quantities of incorrect weld filler metal were recently discovered in fabricated assemblies. The presence of such impurities, which are not detectable using ...
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