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  • Smart Sample Prep in Chromatography: An Automated Liquid–Liquid Extraction Technique for ...

    Friday, February 19, 2016
    Application Note
    Emmanuel Varesio Sandra Jahn Sandrine Cudré Gérard Hopfgartner Renzo Picenoni Guenter Boehm
    As laboratories continue to be asked to increase productivity and the analysis power that is available with advanced chromatography systems continues to grow, the focus for many scientists is firmly ... read more

  • Computer-Assisted Structure Elucidation in Routine Analysis

    Tuesday, January 26, 2016
    Application Note
    Patrick Wheeler Steve Hayward Mikhail Elyashberg
    The elucidation of unknown structures, especially those with novel moieties found in natural products, often results in initially incorrect published structures, which then require either exhaustive ... read more

  • Sample Processing at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... read more

  • How Solid-Phase Extraction Affects Challenges in Bioanalysis

    Wednesday, February 05, 2014
    Application Note
    Mike Oliver Tim Liddicoat Ken Meadows
    Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... read more

  • Product Intelligence: Solid Phase Extraction Systems

    Monday, February 25, 2013
    Technical Article
    Solid phase extraction, or SPE, is used to isolate pollutants in water and pesticides in food, isolate drugs in blood and tissue samples, and separate proteins from a mixture, among other applications... read more

  • Raman and Infrared Spectra: Capturing the Artistry of Spectral Interpretation

    Tuesday, October 02, 2012
    Application Note
    Michael Boruta
    This article focuses on a means of capturing spectrum-to-structure correlations for Raman and infrared spectra. It discusses methods that can be used to obtain, archive, and retrieve this knowledge so... read more

  • Optimizing HPLC Sample Preparation

    Monday, February 06, 2012
    Technical Article
    Caitlin Smith
    Sample preparation is an important component for analysis in high-performance liquid chromatography (HPLC)/ultra high-performance liquid chromatography (UHPLC). This article outlines commonly used ... read more

  • Automated Structure Verification by NMR, Part 1: Lead Optimization Support in Drug Discovery

    Tuesday, January 10, 2012
    Technical Article
    Philip Keyes Michael Messinger Gonzalo Hernandez
    The pharmaceutical industry has always relied on testing and evaluating novel compounds in a wide range of chemical space to feed its pipelines. read more

  • Increased Throughput in Method 8270 Analysis

    Monday, January 01, 2007
    Application Note
    William D. Goodman Frank DeLorenzo
    Method 8270 is a GC-MS method created by the U.S. EPA Office of Solid Waste for the analysis of semivolatile organics by gas chromatography-mass spectrometry. read more

  • Automated Chemical Ionization in GC-MS

    Monday, January 01, 2007
    Application Note
    Chris Sandy Jean-Francois Garnier Bernhard Rothweiler Fred Feyerherm Sihem Ben Mahmoud Harry F. Prest
    Gas chromatography with mass spectrometric detection using chemical ionization (CI) has demonstrated great utility in a wide variety of application areas ranging from forensics to environmental to ... read more
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