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  • Improving the Crystallization Process for Optimal Drug Development

    Friday, March 28, 2014
    Application Note
    Michael Collazo Soheila Vaezeslami Sarah Burl
    Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ... read more
  • Innovation Thrives at the American Society for Mass Spectrometry 2013

    Tuesday, August 06, 2013
    Technical Article
    Paul O Danis
    When J.J. Thomson, the father of mass spectrometry, published his seminal book, Rays of Positive Electricity, 100 years ago, he could not have imagined the vast array of applications that would be ... read more
  • Advances in Mass Spectrometry at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Brian Musselman
    This has been a busy year for mass spectrometry companies and with the Triennial International Conference on Mass Spectrometry occurring last fall. This year at Pittcon®, several new high-end mass ... read more
  • Neutron Crystallography Contributes to Drug Design

    Monday, January 07, 2013
    Technical Article
    Zoe Fisher
    Carbonic anhydrases are a large group of enzymes that are expressed in humans. Carbonic anhydrase (CA) catalyzes the reversible hydration of CO2 to make bicarbonate and a proton. As such, this enzyme ... read more
  • American Society for Mass Spectrometry 2012 Product Showcase

    Tuesday, July 31, 2012
    Technical Article
    Jeanely Hunt, MS, MBA
    Mass spectrometry is a fundamental technique used by chemists and life science researchers for determining unknown samples across various research areas, such as environmental analysis, toxicology ... read more
  • Pittcon® 2012 Roundup of Spectroscopy and Mass Spectrometry

    Monday, May 07, 2012
    Technical Article
    Jeffrey M. Perkel
    This past March, some 15,754 people from 90 countries descended on Orlando, Florida, for the annual Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon®). read more
  • General Laboratory Equipment: Innovation Showcase

    Monday, May 09, 2011
    Technical Article
    Jeanely Hunt, MS, MBA
    Each year, manufacturers and distributors flesh out many innovations for the laboratory, ranging from simple accessories to large, more complex instrumentation. read more
  • Increasing Application of X-Ray Powder Diffraction in the Pharmaceutical Industry

    Wednesday, June 01, 2005
    Application Note
    Brian Litteer Detlef Beckers
    X-ray powder diffraction has recently been propelled to the forefront as an analytical tool in the pharmaceutical industry for a wide range of applications. read more
  • Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov Marina M. Ulyanova Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more
  • Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher Lucie Lorrain Marie-Eve Rouette Elisabeth Perron Nancy Déziel Louis Tessier François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more
  • Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen John S. Seelenbinder Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more
  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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