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  • Transitioning From HPLC to UHPLC of Proteins

    Wednesday, March 09, 2016
    Application Note
    Robert L. Stevenson, Ph.D.
    Since the introduction of ACQUITY UPLC (Ultra Performance Liquid Chromatography) by Waters (Milford, Mass.) over a decade ago, there has been increased interest in the effects of high pressure on ... read more

  • A Simplified Approach to Bioanalytical Sample Preparation

    Wednesday, April 08, 2015
    Application Note
    Erica Pike
    The complexity of biological samples can pose challenges to downstream analysis in the pharmaceutical industry. Bioanalytical and drug metabolism and pharmacokinetics (DMPK) groups often work with ... read more

  • Sample Prep for LC, GC, and SFC at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more

  • Putting the “More” in Morphology: Part 2

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Part 1 of this article discussed the impact of multiplexing morphological methods, multiparametric techniques, and supervised machine-learning to answer the question "what" is there, as well as "where... read more

  • Light-Emitting Diodes: A New Solution for Fluorescence

    Saturday, October 01, 2011
    Technical Article
    Barbara Foster
    From the dramatic increase in new fluorophores to the proliferation of techniques like total internal reflection fluorescence (TIRF), photoactivated localization microscopy (PALM), and stochastic... read more
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