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  • Protein Aggregation at PepTalk 2014

    Monday, March 31, 2014
    Technical Article
    Robert L. Stevenson, Ph.D.
    Quantitative analysis of subvisible particles is an important unsolved problem, as discussed in the Particle Analysis track of PepTalk 2014, held January 12–17 at the Renaissance Hotel and Palm ... read more

  • Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more

  • Direct Improvement With Direct Dilution

    Friday, August 09, 2013
    Application Note
    Joe Olechno Sean Ekins Antony J. Williams Mark Fischer-Colbrie
    The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more

  • High-Content Analysis (HCA 2013): 3-D Reduces the Gap Between In Vitro and In Vivo

    Tuesday, February 05, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The 10th High-Content Analysis meeting attracted about 300 scientists to San Francisco’s Fairmont Hotel (January 8–11, 2013). A Venn diagram of attendees would certainly include overlapping circles ... read more

  • Diagnostic, Prognostic, and Predictive: The Dynamic Role of Molecular Technology in Personalized ...

    Tuesday, January 10, 2012
    Technical Article
    T. Keith Brock
    The expected growth of molecular techniques over the next 10 years will have a profound impact on clinical decision-making. read more

  • Plate Washing in 1536: Evaluation of a Double-Column Aspirator Head

    Thursday, October 22, 2009
    Application Note
    Michelle Batchlett Jason Cassaday Carissa Ohart Kurtis Berry Oleg Kornienko Jim Chang
    Plate assays (1536-well) that require washing (i.e., enzyme-linked immunosorbent assays [ELISAs] and cell-based), are not routinely implemented in high-throughput screening laboratories due to the ... read more

  • Minimizing Liquid Delivery Risk: Operators as Sources of Error

    Saturday, September 01, 2007
    Technical Article
    Wendy Vaccaro
    This is the third in a series of articles entitled “Minimizing Liquid Delivery Risk,” addressing the most common causes of liquid delivery error and providing guidance on how to address and overcome ... read more

  • Increased Throughput in Method 8270 Analysis

    Monday, January 01, 2007
    Application Note
    William D. Goodman Frank DeLorenzo
    Method 8270 is a GC-MS method created by the U.S. EPA Office of Solid Waste for the analysis of semivolatile organics by gas chromatography-mass spectrometry. read more

  • Automated Chemical Ionization in GC-MS

    Monday, January 01, 2007
    Application Note
    Chris Sandy Jean-Francois Garnier Bernhard Rothweiler Fred Feyerherm Sihem Ben Mahmoud Harry F. Prest
    Gas chromatography with mass spectrometric detection using chemical ionization (CI) has demonstrated great utility in a wide variety of application areas ranging from forensics to environmental to ... read more
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