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Why You Should Know about the Excipients Search Tool
Monday, December 01, 2014
The American Pharmaceutical Review Excipients Search Tool is the first commercially accessible search tool featuring the latest excipients available for research and purchase from top excipients ...
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Observations on Regulatory RNAs 2014
Wednesday, October 29, 2014
The last two decades have been exciting times as simplistic genomic models were updated to explain mechanistic details. Along the way, we discarded the expectation that sequencing the genome would ...
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Top Considerations When Automating Your Real-Time PCR Workflow
Thursday, October 16, 2014
With the increasing importance of large-scale data generation, many pharmaceutical labs are using robots to speed data collection. One such strategy is to automate the real-time PCR workflow.
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Semantic Web Technologies as a Key to Successful Federation of Data in Life Science Organizations
Monday, September 22, 2014
The RDF Semantic Web has become an important player over the years in regard to federating different data sources using a common query federation tool, SPARQL. W3C SPARQL is now established as a ...
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Thorough Risk Assessment Supports At-Scale Process Safety
Wednesday, July 16, 2014
It goes without saying that in any manufacturing environment no one sets out to design an unsafe process. However, it is not enough to ensure a process will be safe under normal operating conditions.
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Robert Stevenson Honored by CASSS
Wednesday, June 18, 2014
In recognition of his many years of volunteer service to CASSS, Robert Stevenson, Ph.D., Editor of American Laboratory, was named a Fellow of the Society and recognized by the Board of Directors at a ...
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QA/QC Labs and Smart Infrastructure Equal End-to-End Quality by Design
Friday, June 13, 2014
In his report, “Product Innovation Requires Laboratory Informatics Systems to Transcend Phases,” Gartner analyst Michael Shanler recommends that manufacturers “prioritize end-to-end informatics ...
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Improving the Crystallization Process for Optimal Drug Development
Friday, March 28, 2014
Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ...
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The 7 Most Talked About Pharmaceutical Recalls in American History
Thursday, March 13, 2014
Drug recalls occur when a medicine is pulled out from the market because it has been found to be either faulty or potentially hazardous to health. These recalls can be conducted as the manufacturer’s ...
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Banking on Biologics
Thursday, January 09, 2014
Biologics means big bucks and big rewards. The pharma industry is keen to capitalize on this success as revenues are tipped to reach over $407 billion by 2018.
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Validation of Metal Impurities in Drug Products
Thursday, November 07, 2013
The Elemental Impurities Chapters <232> and <233> were due to appear this year in the U.S. Pharmacopeia (with similar sections in the European Pharmacopeia). The date has now been pushed back pending the 233>232>...
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Automatic Motorized Leveling of Laboratory Balances
Friday, October 04, 2013
A fundamental rule for using high-resolution balances in pharmaceutical laboratories is that the instrument be level at all times. If the lab balance is not level, it cannot accurately measure objects...
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Translational Medicine and the ’Omics Electronic Lab Notebooks
Tuesday, August 06, 2013
Translational medicine research (TransMed) is a new environment in which groups of stakeholders come together to review increasingly complex data with the goals of improving outcomes, getting more ...
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A Novel Sample Preparation Method for Complete Digestion of Complex Pharmaceutical Matrices
Friday, June 07, 2013
For more than 100 years, the USP General Chapter <231> concomitant visual test was the standard method for the determination and quantification of heavy metal impurities present in pharmaceutical products 231>...
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A High-Resolution Look at Glass Delamination Using Transmission Electron Microscopy (TEM)
Tuesday, April 09, 2013
Formation of glass delamination flakes and secondary products through reaction of injectable pharmaceutical solutions with glass vial packaging leads to product contamination and costly recalls. ...
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