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The Deeper You Dig, The More You Find
Tuesday, November 17, 2015
”The deeper you dig, the more you find” is frequently heard in proteomics, particularly at Proteins Powering NexGen Healthcare—Revolutionizing Biomarker Research and Translational Science Symposium: ...
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The Past, Present and Future of Gene Therapy
Thursday, October 01, 2015
Gene therapy to correct disease has intuitive appeal—if a disease is caused by a genetic defect, then repairing the gene should correct it.
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Preview of the 24th International Light Scattering Colloquium: An Interview With Philip Wyatt of Wyatt Technology Corp.
Wednesday, September 30, 2015
Light scattering is the most powerful tool for characterizing the size, shape, interactions and function of nanoparticles.
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Big Data at the 2015 AAPS National Biotechnology Conference
Friday, September 04, 2015
The 2015 AAPS National Biotechnology Conference opened with an extended session on the utility of big data technology in the creation of a modern pharmaceutical industry.
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Boom or Bust?
Thursday, September 03, 2015
Pot is becoming big business. Four states—Colorado, Oregon, Alaska and Washington, as well as the District of Columbia—have legalized the recreational use of marijuana.
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Holistic Lab Review Helps Avoid Out-of-Spec (OOS) Results
Mettler-Toledo Inc.
Thursday, August 20, 2015
Pharmaceutical laboratories are often asked to be more productive despite greater budget restrictions, a situation that can lead to crisis management, as opposed to continual assessment and ...
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Biotechnologists, Take a Bow
Monday, August 03, 2015
Blincyto has a unique mechanism of action, according to Anthony S. Stein, M.D., of the City of Hope Medical Center in Duarte, Calif.
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Use of Transgenic Mouse Models to Test for Carcinogenicity
Tuesday, April 21, 2015
Carcinogenicity studies are conducted to determine the tumorigenic potential of pharmaceuticals and chemicals, as required by regulatory authorities. Two-year bioassays in rats and mice have ...
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Simplified Bioanalytical Sample Preparation
Wednesday, April 08, 2015
The complexity of biological samples can pose challenges to downstream analysis in the pharmaceutical industry. Bioanalytical and drug metabolism and pharmacokinetics (DMPK) groups often work with ...
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Importance of Laboratory Compliance
Friday, April 03, 2015
Before analytical results can be generated, a laboratory requires a suitable calibrated instrument, a trained analyst, an approved/validated method, appropriate reference materials, a standard ...
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Analysis of Hemoglobin Variants using an Automated Sample Preparation Workstation Coupled to LC-MS
Shimadzu
Tuesday, March 03, 2015
Hemoglobinopathies are genetic defects that result in one of the chains of the hemoglobin molecule. These are usually single-gene disorders, such as sickle cell disease, and they are usually ...
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Use of Microcalorimetry to Study Protein Stability
Monday, February 16, 2015
Differential scanning calorimetry (DSC) is used in the pharmaceutical, polymer and biotechnology industries to study the effect of temperature on a variety of solids or liquids, including those that ...
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Analytical Method Development in the Quality by Design Framework
Waters Corporation, AstraZeneca
Tuesday, December 16, 2014
The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ...
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LIMS and the New Monitoring Paradigm for Pharmaceuticals and Personal-Care Products
Tuesday, December 16, 2014
A recent study published in the journal Environmental Pollution identified 56 active pharmaceutical ingredients (APIs) in effluent samples from 50 large wastewater treatment plants across the U.S. ...
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Electrochemical Determination of Acetaminophen Using Gold Nanoparticles–Multiwall Carbon Nanotubes Modified Glassy Carbon Electrode
Sigma-Aldrich Corp
Monday, December 15, 2014
Since their discovery in 1991, carbon nanotubes (CNTs) have been extensively studied for use in emitting devices, energy storage, sensor field, and biological and biomedical applications.
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