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A Microdispenser for LC Separation and MALDI MS Analysis
Saturday, September 01, 2007
Peptide mass fingerprinting (PMF) is a mass spectrometry protein identification technique based on peptide mass detection and is useful for differential expression analysis in the search for drug ...
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Minimizing Liquid Delivery Risk: Operators as Sources of Error
Saturday, September 01, 2007
This is the third in a series of articles entitled “Minimizing Liquid Delivery Risk,” addressing the most common causes of liquid delivery error and providing guidance on how to address and overcome ...
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Statistics in Analytical Chemistry: Part 27—Receiver Operating Characteristic (ROC) Curves
Saturday, September 01, 2007
Consider the following algebraic equation: 5x + 11y + 39z = 106 Since this single expression has three unknowns, there are many possible solutions; a single exact solution cannot be found.
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The Search for Promising Viral Targets in Drug Discovery
Wednesday, August 08, 2007
In the past decade we have seen advances in laboratory automation and in assays used to assess biological endpoints.
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Thermal Analysis of Biodegradable Material: From Modulated Temperature DSC to Fast Scan DSC
Wednesday, August 01, 2007
Synthetic polymers derived from petroleum products are used widely on a daily basis.
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A Novel Electrode Material That Extends the Utility of HPLC–Electrochemical Detection
Wednesday, August 01, 2007
Boron-doped diamond (BDD), a working electrode material developed for use with HPLC–electrochemical detection, promises to open new areas for analysis with electrochemical detectors.
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A New Homogenizing Technology Designed to Save Time, Improve Yield, and Eliminate Cross-Contamination
Wednesday, August 01, 2007
Rotor–stator technology is a highly efficient method utilized by many laboratories to homogenize, disrupt, emulsify,and blend a broad range of samples, including tissue samples.
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Efficient Use of Spectral Information Through Multiline Analysis in ICP-AES
Wednesday, August 01, 2007
The classical way to conduct the determination of an element in inductively coupled plasma-atomic emission spectrometry (ICP-AES) is to select a single line with adequate sensitivity and that is free...
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A Novel Approach for Profiling VOCs in Water Samples Using a Purge-and-Trap Concentrator
Wednesday, August 01, 2007
U.S. EPA drinking water Methods 524 and 8260 implement purge-and-trap (P&T) technology and are widely used by laboratories for the analysis of volatile organic compounds (VOCs).
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A Noninvasive Method for Deep Raman Spectroscopy of Living Tissue and Powders
Wednesday, August 01, 2007
Many analytical applications require fast, noninvasive characterization of deep regions of diffusely scattering (turbid) media, such as living tissue and powders, with high chemical specificity.
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DSC–Microscopy
Wednesday, August 01, 2007
Differential scanning calorimetry (DSC) has been the primary thermal analysis tool since its inception many decades ago.
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Increasing Throughput and Lowering Detection Levels in ICP-MS Analysis Using a Microwave Digestion Quartz Rotor for Sample Preparation
Wednesday, August 01, 2007
Analytical chemists are being asked to perform trace and ultratrace metals analysis on a routine basis.
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Providing Gases for LC-MS Systems in a Safe, Convenient, and Cost-Effective Manner
Wednesday, August 01, 2007
A liquid chromatographic system with a mass spectrometric detector (LC-MS) requires a supply of nitrogen as the curtain gas, pure zero grade air as the source gas, and dry (–40 °F dewpoint) air as the...
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Calorimetry: Getting the Winning Combination
Wednesday, July 18, 2007
Ultrasensitive calorimetric instruments for measuring very small heats of reaction at constant temperature (isothermal titration calorimetry [ITC]) and small heat effects induced by temperature (...
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Multidetection Microplate Readers: Filter-Based, Monochromator-Based. . .or Both?
Friday, June 01, 2007
The appeal of multidetection microplate readers is easy to understand: they combine multiple measurement technologies such as absorbance, fluorescence,and luminescence into one compact instrument.
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