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Direct Improvement With Direct Dilution
Friday, August 09, 2013
The advent of a new technology often brings far-reaching benefits well beyond the initial perception of its key advantages. Acoustic dispensing, for example, with the ability to have highly ... read more
China Catches up in Monoliths for LC
Thursday, August 08, 2013
Almost 20 years ago, I made my first trip to the People’s Republic of China. Over the next decade, I visited many times, working on various commercial ventures, mostly related to chromatography and ... read more
High-Resolution Separation of Nucleic Acid Fragments
Wednesday, August 07, 2013
The invention of the polymerase chain reaction (PCR) in the early 1980s revolutionized molecular biology and molecular medicine. Since then, PCR has developed into a widely used technique for ... read more
A Capillary Gel Electrophoresis Fluorescence System for Antibody–Antigen Interactions
Wednesday, August 07, 2013
Since its inception more than 20 years ago, slab gel-based electrophoresis technology has been used routinely for the analysis of biomolecules (i.e., DNA, proteins, and carbohydrates). However, use of... read more
In Situ Electrochemical SPM for Energy and Corrosion Studies
Wednesday, August 07, 2013
Renewable energy technologies such as solar and wind have been gaining momentum due to a growing awareness of climate change and limited resources (e.g., fossil oils) as well as greater support from ... read more
Innovation Thrives at the American Society for Mass Spectrometry 2013
Tuesday, August 06, 2013
When J.J. Thomson, the father of mass spectrometry, published his seminal book, Rays of Positive Electricity, 100 years ago, he could not have imagined the vast array of applications that would be ... read more
Crossing the Chasm of Death for Biomarkers
Tuesday, August 06, 2013
Biomarkers, or biological markers, have intuitive appeal, since chemists and biochemists are trained to relate activity to molecular structure and metabolism. I attend over 20 scientific meetings per ... read more
Translational Medicine and the ’Omics Electronic Lab Notebooks
Tuesday, August 06, 2013
Translational medicine research (TransMed) is a new environment in which groups of stakeholders come together to review increasingly complex data with the goals of improving outcomes, getting more ... read more
Determination of Total Mercury Content and Trace Metal Analysis in Wood Materials—Part 1: ICP-OES Using Mercury Cold Vapor
Tuesday, August 06, 2013
The transition metal mercury has many exciting properties; for example, it is the only known metal that is liquid at room temperature, hence its use in thermometers. Other common applications are in ... read more
New Drug Development Tools (DDT): Connecting the Dots Between Biomarker Discovery and Improved Patient Outcomes
Tuesday, August 06, 2013
For at least two decades, biological markers, or biomarkers, have been promoted as key advances in scientific discovery that provide a measure of biological function. Researchers and, indeed, the ... read more
Volume 45, Number 7
Monday, August 05, 2013
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A Simple Chip for Circulating Tumor Cells
Monday, August 05, 2013
Circulating tumor cells (CTCs) is a high interest topic. Several methods have been proposed for capturing CTCs, including field flow fractionation and high-performance capillary electrophoresis (HPCE)... read more
The Role of Synthetic DNA in Big DNA and Genetics Research
Friday, August 02, 2013
Synthetic biology is defined as the de novo design and construction of biological devices and systems, and as such is heavily reliant on the use of synthetic DNA. The size and sequence of potential ... read more
Guess the Cover of American Laboratory—August 2013
Thursday, August 01, 2013
Correctly identify this month’s cover image and be entered to win a $10 Amazon gift card read more
Nano Sensors Measure the Wall
Monday, July 29, 2013
Continuous real-time monitoring of critical bioprocesses has intuitive appeal as an improvement over discrete sampling. I was impressed with a paper reporting the development of tattoo electrochemical... read more