Article Archives

Filter

Hide Filter

  • High-Throughput Tools for Optimizing Drug Nanosuspensions

    Thursday, February 19, 2015
    Application Note
    Dennis H. Leung Timothy Rhodes Annette Bak
    Inadequate absorption and bioavailability often make it difficult to deliver the drug to the target in vivo and pose significant challenges to the discovery and development of new drugs. A number of ... read more

  • Improving the Crystallization Process for Optimal Drug Development

    Friday, March 28, 2014
    Application Note
    Michael Collazo Soheila Vaezeslami Sarah Burl
    Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ... read more

  • R&D Informatics at Molecular Med Tri-Con 2013

    Tuesday, February 26, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in... read more

  • Neutron Crystallography Contributes to Drug Design

    Monday, January 07, 2013
    Technical Article
    Zoe Fisher
    Carbonic anhydrases are a large group of enzymes that are expressed in humans. Carbonic anhydrase (CA) catalyzes the reversible hydration of CO2 to make bicarbonate and a proton. As such, this enzyme ... read more

  • Increased Throughput in Method 8270 Analysis

    Monday, January 01, 2007
    Application Note
    William D. Goodman Frank DeLorenzo
    Method 8270 is a GC-MS method created by the U.S. EPA Office of Solid Waste for the analysis of semivolatile organics by gas chromatography-mass spectrometry. read more

  • Automated Chemical Ionization in GC-MS

    Monday, January 01, 2007
    Application Note
    Chris Sandy Jean-Francois Garnier Bernhard Rothweiler Fred Feyerherm Sihem Ben Mahmoud Harry F. Prest
    Gas chromatography with mass spectrometric detection using chemical ionization (CI) has demonstrated great utility in a wide variety of application areas ranging from forensics to environmental to ... read more

  • Increasing Application of X-Ray Powder Diffraction in the Pharmaceutical Industry

    Wednesday, June 01, 2005
    Application Note
    Brian Litteer Detlef Beckers
    X-ray powder diffraction has recently been propelled to the forefront as an analytical tool in the pharmaceutical industry for a wide range of applications. read more
  • <<
  • >>