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The Multidisciplinary Electronic Laboratory Notebook: Pipe Dream or Proven Success?
Tuesday, November 01, 2011
Electronic laboratory notebooks (ELNs) emerged in the R&D landscape around 15 years ago with a commendable objective: reduce or eliminate the errors and inefficiencies driven by the use of paper ...
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Applications of Ion Chromatography in the Public Health Sector and Advances in Chromatography Systems at IICS 2011
Saturday, October 01, 2011
Never before have I attended a meeting that concisely addressed so many topics of current public concern.
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Using MALS-UV-RI Detection for Accurate Characterization of PEGylated Proteins
Saturday, October 01, 2011
PEGylation involves covalent attachment of synthetic polyethylene glycol (PEG) chains to another molecule, usually a protein, peptide, or nucleotide.
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Determination of Association (k
on
) and Dissociation (k
off
) Rates of Spiperone on the Dopamine D2 Receptor Using a Platform for GPCR Applications
Saturday, October 01, 2011
Discussions on the use of the Tag-lite® platform for G protein-coupled receptor (GPCR) applications have revolved solely around affinity or potency and the calculation of the Kd output, greatly ...
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Chromatographic Behavior of Activated Alumina Adsorbents for the Analysis of Hydrocarbons
Saturday, October 01, 2011
Alumina porous layer open tubular (PLOT) columns have long been used for the analysis of volatile hydrocarbons.
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Light-Emitting Diodes: A New Solution for Fluorescence
Saturday, October 01, 2011
From the dramatic increase in new fluorophores to the proliferation of techniques like total internal reflection fluorescence (TIRF), photoactivated localization microscopy (PALM), and stochastic...
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Use of Integrated Data Analysis to Gain an Advantage in Biomarker Discovery and Personalized Medicine
Saturday, October 01, 2011
The genomic revolution of the last two decades has provided pharmaceutical companies with an almost overwhelming number of potential drug targets.
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Statistics in Analytical Chemistry: Part 44—R
2
Saturday, October 01, 2011
Imagine that a new method has been developed and now needs a calibration curve.
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Use of qPCR to Detect Biomarkers for Assessing Stem Cells
Saturday, October 01, 2011
In the human body, undifferentiated stem cells are the raw material used to repopulate tissues and organs in response to accidental cell death or normal cell turnover.
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Can Technology Crack and Extract Useful Knowledge From Proteomics, or is the Proteome too Complex?
Saturday, October 01, 2011
Society has invested tens of billions of dollars in the last two decades to sequence the human genome and look for biomarkers to fight disease and guide therapy.
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Highlights From the 15th International Symposium on Field- and Flow-Based Separations (FFF 2011)
Saturday, October 01, 2011
Field flow fractionation (FFF) suffered through a long, 40-year infancy and is only now entering puberty.
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Simultaneous Determination of Neutral and Anionic Analytes With a Single Column: Method Development Examples Using a Reversed-Phase/Weak Anion Exchange Mixed-Mode Column
Saturday, October 01, 2011
Many samples contain not only neutral hydrophobic analytes, commonly determined using reversed-phase (RP) HPLC, but ionic analytes.
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The Power of Pulsed Amperometric Detection Coupled With Chromatography for Analyzing Carbohydrates
Saturday, October 01, 2011
Most chemists vaguely remember a portion of their instrumental analysis course that covered electroanalytical chemistry.
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Selective Enrichment of Cytoskeleton-Associated Proteins for Detailed Protein Biochemical Analysis
Saturday, October 01, 2011
The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells, including structural support and intra- and extracellular movement.
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Pharmaceutical Supply Chain Management Using Semantic Web Technology: Case Study
Saturday, October 01, 2011
The growing product portfolio of Biogen Idec was resulting in rapid domestic and international expansion, leading to an increasingly complex pharmaceutical supply chain.
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