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  • Methodologies for Stabilization of Pharmaceuticals in Biological Samples

    Friday, July 01, 2005
    Technical Article
    Jiwen Chen Ganfeng Wang Jean-Marc Brisson Yunsheng Hsieh
    The instability of small drug molecules in biological fluids causes serious bioanalytical challenges, regardless of what type of powerful analytical technology is employed for the bioanalytical ... read more

  • Sample Prep for LC, GC, and SFC at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more

  • A Simplified Approach to Bioanalytical Sample Preparation

    Wednesday, April 08, 2015
    Application Note
    Erica Pike
    The complexity of biological samples can pose challenges to downstream analysis in the pharmaceutical industry. Bioanalytical and drug metabolism and pharmacokinetics (DMPK) groups often work with ... read more

  • Transitioning From HPLC to UHPLC of Proteins

    Wednesday, March 09, 2016
    Application Note
    Robert L. Stevenson, Ph.D.
    Since the introduction of ACQUITY UPLC (Ultra Performance Liquid Chromatography) by Waters (Milford, Mass.) over a decade ago, there has been increased interest in the effects of high pressure on ... read more
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